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0Clinical trial of experimental HIV vaccine halted

The National Institute of Allergy and Infectious Diseases has stopped administering an experimental HIV vaccine in the South Africa HVTN 702 clinical trial, after an independent data and safety monitoring board has found that the vaccine is ineffective at preventing HIV infection.

Journal Articles

Bacterial

2020: A molecular odyssey – could artificial intelligence bring in a new age of antibiotic drug discovery?

Technological advances with dressings for wound treatment and detection

Precision medicine in sepsis: where do we begin?

Clostridium Difficile Infection

FDA approves Merck & Co.’s Ebola vaccine Ervebo: January’s industry headlines

IDWeek: Antibiotics before dental visits are overprescribed and increase the risk of side effects

Transkingdom interactions: elevated levels of fungi observed in Clostridium difficile infection

E. Coli

Antibodies from maternal microbiota could protect newborns from infection

Multidrug efflux systems: information on evolution and mechanisms uncovered

E. coli created with world’s first synthetic and redesigned genome

H. Pylori

Organoids: a new model to study infectious diseases?

Infographic: The microbiome and infectious diseases

Are flies a significant method of bacterial transmission?

MRSA

New study reveals how the household environment influences MRSA spread

Novel vaccine candidate for Staphylococcus aureus shows 80% efficacy in mice

MRSA killed by potent bacterial toxin lysostaphin, study reports

Salmonella

Whole-genome sequencing of Salmonella enterica Serovar Typhi reveals new antimicrobial resistant isolates

Novel models for enteric infections – an interview with the Faherty Lab

Infographic: The burden of foodborne diseases

Tuberculosis

Changing the administration of the BCG vaccine could improve efficacy

WHO prequalifies Ebola vaccine: November’s industry headlines

Harnessing RNA sensors inhibits growth of tuberculosis bacterium

Fungal

A peek behind the paper – Elvira Román on CRISPR technology in pathogenic fungi

The best of 2019 – an A–Z of infectious diseases research

A peek behind the paper – Shujuan Sun on using existing antibiotics as antifungals

Aspergillosis

Fungal biofilm morphology impacts disease progression

#TalkFungi – catch up on the Twitter chat for Fungal Awareness Week

Novel antifungal presents opportunities for treating aspergillosis

Candidiasis

A peek behind the paper – Elvira Román on CRISPR technology in pathogenic fungi

A peek behind the paper – Shujuan Sun on using existing antibiotics as antifungals

Could climate change have contributed to Candida auris emergence?

Coccidioidomycosis

#TalkFungi – catch up on the Twitter chat for Fungal Awareness Week

Identification of membrane proteome of Paracoccidioides lutzii and its regulation by zinc

CNS fungal infections

Cryptococcal Meningitis

#TalkFungi – catch up on the Twitter chat for Fungal Awareness Week

Cryptococcal meningitis – taking a closer look at treatment

Infographic: Fungal infections – the hidden burden

Parasitic

Novel parasites and understanding parasite–host interactions – an interview with Sandra Maruyama

The best of 2019 – an A–Z of infectious diseases research

World Malaria Report 2019: a focus on pregnant women and children

Helminthic Infections

Conference report – London Centre for Neglected Tropical Disease Research Anniversary Event

ISNTD – Female Genital Schistosomiasis: The most neglected gynaecological disease

Conference report – British Society for Parasitology Autumn Symposium

Malaria

World Malaria Report 2019: a focus on pregnant women and children

WHO prequalifies Ebola vaccine: November’s industry headlines

Imaging study reveals how malaria parasites bypass antimalarial drugs

Neglected Tropical Diseases

Novel parasites and understanding parasite–host interactions – an interview with Sandra Maruyama

Mice, introduced by maritime trade, play a key role in Toxoplasma gondii distribution

Diagnostics for human schistosomiasis: the way forward

Protozoan Infections

World Malaria Report 2019: a focus on pregnant women and children

Imaging study reveals how malaria parasites bypass antimalarial drugs

Have scientists identified how P. falciparum jumped hosts 50,000 years ago?

Viral

AGO4: a potential new universal target for antiviral therapeutics

A peek behind the paper – Blake Max on HIV integrase inhibitors

Clinical trial of experimental HIV vaccine halted

Hepatitis

FDA approves Merck & Co.’s Ebola vaccine Ervebo: January’s industry headlines

US FDA warns of serious liver injury linked to hepatitis C drugs: September’s industry headlines

BioMalPar XV: Biology and Pathology of the Malaria Parasite

Herpes

ASM Microbe: What consequences could lifelong Epstein–Barr virus infection have for the brain?

HR-HPV oral infection rates in England are lower than expected

A peek behind the paper – Lynn Enquist on the lifecycle of alpha herpesvirus