Latest News
A new study has investigated the effects of commonly used topical antimicrobials on the skin microbiome, discovering that antibiotics have a major and long-lasting effect.
A team from Tel Aviv University have developed hybrid bacteriophage particles that may allow DNA transduction to new bacteria, expanding the range of currently used phages.
Researchers have identified a subpopulation of T cells as key cytokine producers in addition to proposing a novel mechanism of immunosuppression following superantigen exposure.
Journal Articles
This article discusses evidence for phage engagement in regulating immunity, shedding new light on the potential immunoregulatory activities of phages which constitute an abundant part of the microbiome.
In this review, the authors discuss recent findings on unfolded protein response (UPR) induction/modulation by intracellular parasites in host cells.
As part of the authors ongoing research efforts dedicated to the discovery of novel cruzain inhibitors, a series of benzimidazole derivatives was used to develop predictive 2D and 3D quantitative structure–activity relationship (QSAR) models.
Bacterial
Could topical antibiotics have long-term effects on the skin microbiome?
Clostridium Difficile Infection
ECCMID17: DNA fingerprinting suggests food may be a source of C. difficile
E. Coli
Could bioelectricity help regulate the innate immune system?
ECCMID17: New test could detect colistin resistance in bacteria
Bacteriophages provide promising results against multidrug-resistant E.coli
H. Pylori
MRSA
Could topical antibiotics have long-term effects on the skin microbiome?
Research suggests novel mechanism of superantigen-induced pathology
ASM Microbe: Study demonstrates a decrease in resistant S. aureus in US hospitals
Salmonella
How can nanosensors detect bacterial contamination before it ever reaches the dinner table?
Host–pathogen interactions: how do pathogens escape the process of autophagy?
WHO publishes list of antibiotic-resistant bacteria most in need of new antibiotics
Tuberculosis
Could vitamin A levels affect tuberculosis risk?
Interleukin-37: a new molecular target for host-directed therapy of tuberculosis
Could targeting bacterial metabolism reduce treatment times for tuberculosis?
Fungal
Small-molecule antifungal compound identified for C. albicans
Study examines population genomics in Cryptococcus neoformans
Aspergillosis
Candidiasis
Small-molecule antifungal compound identified for C. albicans
From drug developer to antibiotic hunter – an interview with Mark Blaskovich
Loss of immune control in HIV-infected patients: how does mucosal candidiasis occur?
Coccidioidomycosis
Cryptococcal Meningitis
Study examines population genomics in Cryptococcus neoformans
From drug developer to antibiotic hunter – an interview with Mark Blaskovich
New production method could increase the availability of treatment for cryptococcal meningitis
Parasitic
Endoplasmic reticulum stress and unfolded protein response in infection by intracellular parasites
The London Centre for Neglected Tropical Disease Research – an interview with Sir Roy Anderson
Helminthic Infections
The London Centre for Neglected Tropical Disease Research – an interview with Sir Roy Anderson
Nodding syndrome: pathology and prevention – an interview with Robert Colebunders
Malaria
Variation in red blood cell receptors may confer malaria resistance
Malaria during pregnancy may alter babies’ risk of later infection
Exploration of thiaheterocyclic hHDAC6 inhibitors as potential antiplasmodial agents
Neglected Tropical Diseases
The London Centre for Neglected Tropical Disease Research – an interview with Sir Roy Anderson
Protozoan Infections
Endoplasmic reticulum stress and unfolded protein response in infection by intracellular parasites
Variation in red blood cell receptors may confer malaria resistance
Clinical development of RTS,S/AS malaria vaccine: a systematic review of clinical Phase I–III trials
Viral
Hepatitis B pre-genome RNA may promote nucleocapsid assembly
Hepatitis
Hepatitis B pre-genome RNA may promote nucleocapsid assembly
Modeling in hepatitis – still a long way to go
IDHTalks from ECCMID17: Researching hepatitis – an interview with William Irving
Herpes
Targeting Epstein–Barr virus in multiple sclerosis – an interview with Michael Pender
Varicella zoster virus tissue tropism – a target in vaccine development
Targeting the human TREX complex to prevent herpesvirus replication: what is new?