Latest News
Researchers have successfully reported a case where a 68-year old diabetic patient was successfully treated with a personalized bacteriophage-based treatment. The patient suffered from necrotizing pancreatitis that had previously been unresponsive to routine antibiotic treatment.
A new mathematical modelling study has estimated the mortality rates of TB in the pediatric population, producing the first ever estimate for infants under 5 years of age.
Novel research suggests that type III interferon-mediated signalling could play a major role in controlling live-attenuated yellow fever virus infection in mice.
Journal Articles
Resistance to Naphthoquine has been found in mouse models and might emerge in future as widely used. In this article, the in vivo antimalarial activity of novel naphthoquine derivatives is assessed revealing promising antimalarial candidates for further research.
Inappropriate use and overuse of antibiotics are among the most important factors in resistance development, and effective antibiotic stewardship measures are needed to optimize outcomes.
The pathogenicity of T. marneffei depends on the ability of the fungus to survive the killing process and replicate inside the host macrophage cells. This paper summarizes factors relating to the stress responses that contribute to the intracellular survival of T. marneffei
Bacterial
Phage therapy shows promise against multidrug-resistant bacterial pathogens
Clostridium Difficile Infection
Are cases of recurrent Clostridium difficile infection on the rise in the United States?
ECCMID17: DNA fingerprinting suggests food may be a source of C. difficile
E. Coli
Mechanosensing in E. coli – similarities with vertebrates uncovered
Study reveals copper-transporting function of yersiniabactin in bacteria
Could bioelectricity help regulate the innate immune system?
H. Pylori
MRSA
DNA sequencing could predict MRSA infection outcome
Did MRSA emerge before the introduction of methicillin?
Assessing antibiotic resistance – an interview with Patrick Harris
Salmonella
A novel antimicrobial approach based on the inhibition of zinc uptake in Salmonella enterica
How can nanosensors detect bacterial contamination before it ever reaches the dinner table?
Tuberculosis
New study estimates TB mortality rates in children under 5
Assessing antibiotic resistance – an interview with Patrick Harris
Novel mechanism for cell division identified in mycobacteria
Fungal
Understanding molecular causes of antifungal resistance in A. fumigatus
From Aspergillus to antifungal resistance – an interview with Cornelia Lass-Flörl
Aspergillosis
Understanding molecular causes of antifungal resistance in A. fumigatus
From Aspergillus to antifungal resistance – an interview with Cornelia Lass-Flörl
Candidiasis
From Aspergillus to antifungal resistance – an interview with Cornelia Lass-Flörl
Coccidioidomycosis
Cryptococcal Meningitis
Infographic: Fungal infections – the hidden burden
Study examines population genomics in Cryptococcus neoformans
Parasitic
Microfluidic device could assess hemolytic anemia in malaria
Helminthic Infections
The London Centre for Neglected Tropical Disease Research – an interview with Sir Roy Anderson
Nodding syndrome: pathology and prevention – an interview with Robert Colebunders
Malaria
Microfluidic device could assess hemolytic anemia in malaria
Neglected Tropical Diseases
Protozoan Infections
Microfluidic device could assess hemolytic anemia in malaria
First large-scale study uncovers malaria gene function and potential drug targets
Viral
Yellow fever virus: new insights into the immune signalling pathways that control infection
First 3D movie of virus depicts key biological processes in replication
Hepatitis
Hepatitis B pre-genome RNA may promote nucleocapsid assembly
Herpes
Targeting Epstein–Barr virus in multiple sclerosis – an interview with Michael Pender
Varicella zoster virus tissue tropism – a target in vaccine development
Targeting the human TREX complex to prevent herpesvirus replication: what is new?