Original Publication Date: 8 May, 2017
Publication / Source: Future Microbiology
Authors: Shatzkes K, Connell ND & Kadouri DE
Antibiotics are primarily responsible for the sharp decline of infectious disease-related deaths caused by bacteria over the past 50 years. However, due to the overuse and misuse of antibiotics, among other reasons, the rise of multidrug-resistant (MDR) bacterial infections over the last decade now represents a serious threat to public health. The CDC estimates over 2 million people are infected and more than 23,000 die annually in the USA as a direct result of an MDR infection . Compounding this issue is the fact that an antibiotic discovery void over the past 30 years has resulted in a current shortage in the antibiotic development pipeline.