Is inflammation responsible for neurocognitive impairments in cART-treated HIV?

Researchers have studied macaque models of antiretroviral-treated HIV, discovering that persistent inflammation may underlie neurocognitive impairments in humans.

Combination antiretroviral therapy (cART) has improved the survival of many HIV-infected patients and has also reduced the incidence of neurological complications. However, almost half of cART-treated patients still experience some degree of neurological impairment.

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