ASM Microbe: Drug-resistant hypermucoviscous Klebsiella pneumoniae identified in the USA

A strain of carbapenem-resistant, hypermucoviscous Klebsiella pneumoniae with colistin heteroresistance and enhanced virulence has been isolated from a patient in the USA, according to research presented at ASM Microbe (7–11 June, Atlanta, GA, USA).

Carbapenem-resistant enterobacteriaceae, of which K. pneumoniae is a part, are high on the priority pathogens list and are considered an urgent threat by the Centers for Disease Control and Prevention (CDC; GA, USA). In addition, it is known that hypervirulent/hypermucoviscous variants of K. pneumoniae (hvKP) cause increased mortality and morbidity in immunocompetent patients. The convergence of these two traits has long been a cause for concern, particularly following a recent outbreak of carbapenem-resistant hvKP in China, which led to five deaths.

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