Gonorrhea: does gender matter?

In a recent study published in mSphere, scientists from Tufts University School of Medicine (MA, USA) conducted the first complete comparison of gonococcal gene expression and regulation in both women and men. The researchers identified gender-specific signatures in antibiotic resistance genes as well as differences in the course of infection between men and women.

“We built on our earlier work on gene expression during infection in females to include both genders in the present analysis, so we see for the first time the expression profiles during active disease in males and their asymptomatic partners,” stated the senior author of the study Caroline Genco from Tufts University School of Medicine.

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