Pseudomonas aeruginosa: novel insights into how bacterium causes sickness

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A research team from Binghamton University (NY, USA) have published their findings in the Journal of Biological Chemistry revealing the mechanism by which Pseudomonas aeruginosa, and perhaps other Gram-negative bacteria, communicate to induce toxin delivery that cause sickness in those infected.

Researchers wanted to investigate bacterial communication through small molecule transportation and used a computational model to visualize detailed communication molecule interactions.

“It’s hard to see the molecular detail at that level,” explained Jeffrey Schertzer, Binghamton University. “But with Dr Yong’s expertise, we were able to build a computational model that helped us understand what actually goes on between individual molecules.” 

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