Authors: Martha Powell, Future Science Group
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Today’s news
Pick of the Posters
1. Is maternal plasma Zika virus (ZIKV) load associated with birth outcomes and maternal disease severity? by Pellerin S. from INSERM (France), assess a cohort of women from the 2016 Zika outbreak in the French West Indies concluding that higher plasma ZIKV load was associated with a more severe maternal ZIKV infection; however, no relationship was observed between viral load and neurological birth defects.
2. The oropharyngeal (OP) microbiome of hospitalised patients: A potential contributor to pneumonia risk, by Ashokan A from the South Australian Health and Medical Research Institute (Australia) assessed OP swabs from 63 patients and 79 controls, all of which underwent genomic DNA extraction and 16S rRNA sequencing, concluding that there were significant differences between the OP microbiome in hospitalized individuals compared with a healthy cohort. However, whether OP microbiota characteristics have a clinical utility in predicting lower respiratory tract infections in this population warrants investigation.
Best of social media #ECCMID19
In reality, antibiotic resistance is not an all or nothing thing – it’s much more complicated #ECCMID2019 pic.twitter.com/1CkfMvEKix
— Jonathan Sandoe (@j_sandoe) April 13, 2019
.@bdubrx sharing his work on translational PK/PD modeling of dalbavancin terminal PK and resistance development in S. aureus. The terminal t1/2 of dalba leading to conc above MIC90 for >12 wks led to resistance to VAN, DAP, and DALBA in the model @SIDPharm #ECCMID2019 pic.twitter.com/t5WcKiNSTG
— Ryan Crass (@Crasspofungin) April 13, 2019
@FernandoDocobo presenting now on methods for resistance testing in GNR. Important in testing for heteroresistance. “Phenotypic heterogeneity is the rule not the exception” over-reliance on MIC noted #ECCMID2019 pic.twitter.com/9ITUX7Iluf
— David van Duin (@davidvanduin) April 13, 2019
The term ‘intermediate’ often lumped with ‘R’ , but it is something quite different. So we have to find a way to #communicate with clinicians about the right definiton of intermadiate.
For the standard and increased exposure regiments take a look at EUCAST v.9.0#ECCMID2019 pic.twitter.com/L8auOGCcFu— Trainee Association of ESCMID (@TAEscmid) April 13, 2019
