Neutralizing antibody shows promise for norovirus vaccine

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A study published in Immunity has identified a neutralizing antibody that binds to a highly conserved epitope in a pandemic strain of norovirus, in a potential step towards the development of an effective norovirus vaccine.

Human norovirus strains are the leading cause of gastroenteritis and responsible for 200,000 deaths every year. Researchers from the University of North Carolina at Chapel Hill (NC, USA), in collaboration with teams from the University of Texas at Austin (TX, USA) and the National Institutes of Health Vaccine Research Center (MD, USA), have discovered an antibody that inhibits multiple strains of norovirus.

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