Authors: Alex Hyde (Future Science Group)
Researchers at Stanford University (CA, USA) and the University of California-San Francisco (CA, USA) have identified a single protein that is critically important for viral infection by a large range of enteroviruses (EVs), including rhinoviruses and non-polio EVs. Temporarily disabling this single protein could protect humans from infections ranging from the common cold to non-polio EVs that have been increasingly linked to severe neurological diseases.
Previously, targeting host proteins has been used to stop viruses associated with asthma, encephalitis and polio. In this research, published recently in Nature Microbiology, the use of genome-scale CRISPR screening to identify SETD3 as a critically important protein for viral infection is described.