Novel vaccine candidate for Staphylococcus aureus shows 80% efficacy in mice

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Published today in Infection and Immunity, researchers have identified a novel vaccine for Staphylococcus aureus, which has demonstrated 80% efficacy in mouse and rabbit models.

Hospital-acquired S. aureus infections result in 30,000 deaths annually, with an upper mortality rate of approximately 30%, in cases of bacteremia. With over 70 virulence factors and rapid biofilm formation, S. aureus is highly resistant to the host immune response as well as many antibiotics.

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