What effect will SARS-CoV-2 variants have on vaccine efficacy?

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The ‘inevitable’ domination of novel SARS-CoV-2 variants from Brazil, South Africa and the UK could result in less effective COVID-19 vaccines and drugs, designed with the original virus form in mind.

Researchers from Washington University School of Medicine (WA, USA) have published a study indicating that novel SARS-CoV-2 variants can evade antibodies that target the original form of the virus. The study discovered that more antibodies are needed to neutralize these variants, regardless of the antibody origin – from vaccination, natural infection, or therapeutic antibodies, with few exceptions.

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