Gene atlas of malaria parasite reveals potential drug and vaccine targets

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Scientists from Imperial College London (UK) and the Wellcome Sanger Institute (Cambridge, UK) have mapped the genetic changes malaria parasites go through as they prepare to infect people.

A team led by Eliana Real (Imperial College London), in collaboration with colleagues from the Wellcome Sanger Institute, used single-cell transcriptomics to map gene activity across the transmission cycle of Plasmodium falciparum, often regarded as the deadliest parasite in humans. The atlas could lead to the identification of drug targets that could stop malaria transmission and potentially prevent the disease.

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