Antifungal drugs work together to treat germs causing fungal infections


Candida auris is a fungus often found in the hospital environment that can cause life-threatening infections, and has attracted increased clinical attention because of its multiple drug resistance.

This study looked at how effectively different drugs could treat a C. auris infection. The study collected samples from 36 individuals with a C. auris infection, and treated these samples with either a single drug, or a combination of drugs. The researchers found that the main drug types did not work on most samples. However, they found that a drug called isavuconazole worked on almost all samples, and a drug called anidulafungin worked better against C. auris when it was combined with either isavuconazole or another drug called voriconazole. The researchers also found genetic differences in the C. auris samples, which could explain why the main drugs did not work.

This Plain Language Summary of Publication summarizes the research article, originally published in Antimicrobial Agents and Chemotherapy, without the use of technical language, therefore making the research accessible to patients, their caregivers and healthcare professionals who give or receive treatment for infection with C. auris.

Read the full Plain Language Summary, ‘Antifungal drugs work together to treat germs causing fungal infections’, on the link below.

Antifungal drugs to treat candida auris

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