New research has identified four novel sepsis phenotypes, suggesting these could be relevant for understanding the heterogeneity of treatment effects and help to explain recent clinical trial failures.
Browsing: Disease Area > Bacterial
Based on the demonstrated potential of laser-induced vapor nanobubbles to treat bacterial biofilm infections, we provide recommendations for future work in order to further mature this new technology into a promising anti-biofilm approach.
Scientists have created the world’s first living organism that has a synthetic and altered genetic code, built on only 61 codons as opposed to 64.
Giving a single dose of preventative antibiotics after assisted childbirth could prevent almost half of maternal infections and also reduce antibiotic use by infection prevention, according to a new trial.
A new anaerobic organ-on-a-chip model has been demonstrated to support a complex community of gut microbes under low-oxygen conditions. This model of the microbiome could open opportunities for drug testing and development.
Phage therapy using genetically engineered bacteriophages has treated a 15-year-old girl who developed a drug-resistant infection following a lung transplant, as outlined in Nature Medicine.
Antibiotic tolerance significantly reduces antibiotic efficacy and contributes to treatment failure; targeting both antibiotic tolerance and antibiotic resistance is critical to develop new antimicrobial strategies that will successfully eradicate hard-to-treat infections.
New research has suggested that a combination treatment of gentamicin with azithromycin was almost as effective as the currently used ceftriaxone for treating genital gonorrhea.
Men and women have different risks of developing surgical site infections depending on the type of operation they undergo, according to new research being presented at ECCMID.