Researchers have discovered that a relatively ancient drug efflux pump from Haemophilus influenzae exports the same antibiotics as its evolved counterpart from Escherichia coli, but was mitigated by a leaky porin channel.
Browsing: Bacterial > E. Coli
Scientists have created the world’s first living organism that has a synthetic and altered genetic code, built on only 61 codons as opposed to 64.
Microbiome metabolites have been discovered to enhance colon injury in human EHEC infections in a human–mouse comparative study, accounting for species-specific differences in infection tolerance.
Researchers from the University of Zurich have discovered that thanatin, a compound produced naturally by the spined soldier bug, could target Gram-negative bacteria by preventing formation of the bacteria’s outer membrane – an unprecedented mechanism.
Researchers from the Okinawa Institute of Science and Technology have developed a method to study biofilm formation, and how it is affected by drugs, with high efficacy.
In line with our July focus around enteric infections, we recently spoke to Christina Faherty and Research Fellow from her lab, Alejandro Llanos-Chea, about the lab’s research on Shigella, Salmonella and E. coli and novel models for these in vitro.
In this interview, take a look behind the scenes of a recent Future Microbiology paper on the role of transition metal control in E. coli virulence with author, Jeffrey Henderson.
Small-molecule compounds designed to tag the cell surface of Gram-negative bacteria and trigger an immunological response have shown promise.