The WHO has released its first surveillance data on antibiotic resistance, revealing that it is widespread across both low-income and high-income countries.
Browsing: Bacterial > E. Coli
This research, published in Future Microbiology, screens host proteins for those that interact with EspF via flow cytometry and high-throughput screening to try and shed light on how EspF affects host cells to induce colitis and even colorectal carcinogenesis.
In a recent study published in Nature Communications, researchers demonstrated that acquired resistance to the polymixin antibiotic, colistin, can be detrimental to bacterial survival, revealing unique evolutionary trade-offs of this new form of resistance.
Researchers have demonstrated that antibiotic-resistance plasmids persist in the absence of antibiotics, provided that the efficiency of plasmid transfer exceeds a critical threshold, highlighting the limitations of ‘resistance-reversal’ strategies.
Researchers have analyzed the microbiomes of flies, suggesting that these insects could have more disease-carrying potential than previously thought.
Researchers have unveiled novel pathways controlled by the multiple antibiotic resistance operon and identified new ways in which bacteria protect themselves against antibiotics.
In this infographic we summarize the clinical candidates reported by the WHO – indicating which diseases they are active (or possibly active) against, whether they’re considered innovative and which Phase the trials are currently in.
In this piece, the authors give an overview of anti-virulence drugs, designed to selectively target key virulence factors of pathogenic bacteria, and one strategy for new antimicrobials.
Scientists have unveiled the molecular architecture of two key proteins required for bacillus cell wall elongation. Inhibiting their interaction could provide a new mode of action for antibiotics against highly resistant bacteria.