Researchers have discovered that a leaderless intercellular peptide signal may contribute to group A Streptococcus virulence; providing a framework for the identification in other microorganisms that may potentially serve as therapeutic targets.
Browsing: Disease Area > Bacterial
In this review, the authors consider phage therapy that can be used for treating bacterial infections in humans, domestic animals and even biocontrol in foods. They also explore common practice – both experimental and, in certain regions of the world, clinical – of mixing therapeutic phages into cocktails consisting of multiple virus types.
New research displays how intestinal microbiota could regulate body composition; providing an insight into the molecular link between gut microbiota and the circadian clock via transcription factor NFIL3.
Researchers have pinpointed the four key pathogens responsible for diarrheal disease, a number one cause of morbidity among young children in sub-Saharan Africa and South Asia, highlighting the possible interventions available.
More than a century after its description and the discovery of the bacterial etiological agent, and despite its major burden globally, leptospirosis remains largely under-recognized.
In this column author, Julie Kaiser, explores two recent studies that have highlighted how prior antibiotic exposure can influence the later occurrence of resistance to other antibiotics in Pseudomonas aeruginosa.
A new article has assessed the market penetration of a molecular TB test, Xpert MTB/RIF®, revealing that implementation in high-burden countries has progressed well, but there is more to be done.
Researchers have identified that the combination of aztreonam, amikacin and polymyxin B may possess the ability to eradicate a previously immune strain of Escherichia coli, MCR1_NJ.
We speak to Rebecca Prevots, from the National Institute of Allergy and Infectious Diseases, who discusses her current research projects, the importance of epidemiology in studying infectious diseases and also the challenges this field currently faces.