In this review the authors discuss evidences suggesting that bacterial zinc homeostasis represents a promising target for new antimicrobial strategies, focusing on the inhibition of zinc uptake in Salmonella enterica.
Browsing: Disease Area > Bacterial
New research investigating the evolutionary origins of MRSA has suggested strains may have emerged long before methicillin was used in clinical practice.
Researchers examining brains from healthy and Alzheimer’s subjects have discovered a higher overall presence of Actinobacteria (Propionibacterium acnes) suggesting that bacterial presence may contribute to the disease.
Widespread use of antibiotics in pregnancy to eradicate Group B Streptococcus has reduced disease in babies, however, could bacteriophage therapy yield the same results but in a more selective manner?
New research suggests that blood vessels are unable to clear infection due to the lack of ubiquitination that takes place in the endothelial cells.
Recently, the use of small molecules produced by bacteria became a prominent strategy of biofilm dispersal. Here, the authors discuss small molecules that interfere with biofilm formation, focusing on the complex mode of action and applications of D-amino acids.
Following a warning from the WHO about concerning antibiotic resistance in gonorrhoea, a vaccine originally developed for meningitis has shown promise for protecting against this disease.
After the WHO published data highlighting a concerning level of antibiotic resistance in strains of gonorrhoea, take a closer look at the three antibiotics currently in clinical trials for this pathogen.
The WHO has reported increasing drug resistance in gonorrhoea, with some cases untreatable by current antibiotics, and stated that new drugs are urgently required.