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Countries with previous TB vaccine coverage show improved COVID-19 outcomes
An epidemiological study has revealed that COVID-19 outcomes are better in those countries that have undertaken a TB vaccination regime in the last 15 years.
Browsing: Bacterial > Tuberculosis
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The role of humoral immunity in TB defense – an interview with Babak Javid
Emerging evidence has suggested that B cells and humoral immunity could modulate the immune response to intracellular pathogens. We speak to Babak Javid about his research on this topic and the importance of learning about immune factors in order to develop vaccination strategies and to understand latent TB.
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Changing the administration of the BCG vaccine could improve efficacy
Administering the BCG vaccine intravenously, as opposed to intradermally, could improve the efficacy of the immunization according to new research in macaque models.
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WHO prequalifies Ebola vaccine: November’s industry headlines
Take a look at this month’s industry headlines including results for Takeda’s dengue vaccine, approvals for Merck’s Ebola vaccine and the advent of a siderophore antibiotic – the first of this kind.
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Harnessing RNA sensors inhibits growth of tuberculosis bacterium
New research indicates that harnessing RNA sensors could allow human cells to be more attuned to killing tuberculosis, presenting an effective means for controlling the spread of the disease.
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Clinical trial reveals promising tuberculosis vaccine candidate
A clinical trial conducted in sub-Saharan African countries over 3 years, has revealed a candidate vaccine for tackling tuberculosis. The candidate vaccine, M72/AS01E, was reported to be 54% effective at preventing active pulmonary tuberculosis disease.
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Highlights of the Global Tuberculosis Report: more people receive treatment than ever before
In 2018 more people received treatment for tuberculosis than ever before, largely due to improvements in detection and diagnosis, according to the latest Global Tuberculosis Report from the WHO.
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Antacid helps tuberculosis persist in macrophages
New research has uncovered that Mycobacterium tuberculosis releases an antacid that remodels phagosomes, preventing immune cells from destroying the bacteria.
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US FDA approves Pretomanid tablets for drug-resistant tuberculosis
The US FDA has approved Pretomanid tablets in combination with bedaquiline and linezolid for the treatment of specific types of drug-resistant pulmonary tuberculosis.
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Novel blood test for tuberculosis could also identify high risk of infection
A novel phage-based blood assay has demonstrated its potential for identifying people at high-risk of developing tuberculosis, in addition to diagnosing established cases.