The pathogenicity of T. marneffei depends on the ability of the fungus to survive the killing process and replicate inside the host macrophage cells. This paper summarizes factors relating to the stress responses that contribute to the intracellular survival of T. marneffei
Browsing: Disease Area > Fungal
Take a look at our infographic to find out more about the burden of some common fungal infections and assess why the facts and figures are so uncertain.
In this IDHTalks podcast we speak to Mahmoud Ghannoum about the importance of fungi, his work in identifying mycobiome and its implications in health and disease.
Researchers have uncovered a therapeutic delivery method for nitric oxide in the treatment of dermal Trichophyton rubrum dermatophytosis; providing an alternative treatment to the systemic therapies currently used.
The use of biomarkers for the detection of fungal infections is of interest to complement histopathological and culture methods. Could chemically synthesized Galactofuranose antigens, reviewed in this paper, be used for the synthesis of artificial carbohydrate-based antigens and in diagnosis?
Researchers have reported a small-molecule inhibitor of Candida albican protein Bdf1 and demonstrated the compound yields decreased fungal viability, suggesting a possible future antifungal.
Researchers have examined the complex interaction between environmental pressures and human virulence in Cryptococcus neoformans, demonstrating some variants associated with clinical isolates.