Scientists have revealed proteins, termed RIFINs, expressed on the surface of infected erythrocytes that may help the malaria parasite to suppress the host immune response, leading to severe infection.
Browsing: Parasitic > Protozoan Infections
For the first time researchers have cloned and characterized NANP-reactive memory B-cell antibodies in humans, which have the ability to potently inhibit parasite transmission in vivo.
Researchers have carried out the largest genetic study of Anopheles gambiae, discovering the spread of resistance and high genetic diversity.
Researchers have discovered endemic malaria infection in a geographically-restricted set of wild bonobos, including a possible new species of the parasite.
Researchers have discovered that individuals infected with malaria exhale specific compounds, which could be used to rapidly and accurately diagnose the disease.
Researchers have uncovered five new targets for malaria vaccine development, suggesting that targeting multiple steps of erythrocyte invasion is more likely to produce an effective vaccine.
The spread of a single multi-drug resistant Plasmodium falciparum lineage to south Vietnam has caused alarm after worrying treatment failure rates. Researchers suggest this presents a serious concern for malaria control efforts.
Editor, Martha Powell, discusses the issues around the current guidance for treating HAT and gives an overview of the current clinical pipeline being spearheaded by the Drugs for Neglected Diseases initiative.
Maternal microchimerism (MMc) is a normal part of pregnancy, however, relatively little work has been done exploring the intersection of MMc and infectious disease. Here, Whitney Harrington discusses it’s implications in malaria.