Researchers have developed a novel compound, L-HIPPO, which can prevent viral budding in HIV-infected cells. It has been suggested this compound could supplement existing ‘kick and kill’ strategies, allowing complete eradication of HIV in the body.
Browsing: Viral > HIV / AIDS
A novel trispecific antibody has been developed by researchers from the NIH and Sanofi, demonstrating effectiveness against of 99% of HIV strains and protective immunity in non-human primates.
Researchers have identified the mTOR pathway as a ‘druggable’ key regulator of HIV-1 persister reservoirs in gut-homing CD4+ T cells.
Data from Population-based HIV Impact Assessments in five African countries have demonstrated promising progress towards controlling the HIV epidemic by 2020, however, they have also highlighted gaps.
Evidence has emerged suggesting a link between certain hormonal contraceptives and HIV acquisition risk. This article reviews the epidemiologic studies and potential biologic mechanisms evaluating the association between hormonal contraceptive methods and HIV risk.
Researchers have identified a new treatment approach for acute HIV-infected patients, which targets human proteins rather than the virus.
Researchers have reported that 86% of heterosexuals at high-risk for HIV would use a home-based testing kit sent by post, and almost all of these individuals would seek medical advice following a positive result.
A child born with HIV has been found to suppress the infection without the reliance on conventional antiretroviral therapy; this may have future implications on the therapeutic approaches to HIV especially in infants.
A vaginal ring, hoped to prevent HIV, has been reported to be safe and acceptable in a US study examining use in teenage girls, a particular risk group for this virus.
Results from the early-stage APPROACH trial have demonstrated an investigational HIV vaccine regimen, based on mosaic vaccines, has been well-tolerated and immunogenic in healthy participants.