Researchers have analyzed the clinical characteristics of Zika infection in Canadian travelers returning from the Americas, discovering that severe complications might be more common than previously estimated.
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Researchers have suggested that disease “superspreaders” may have been responsible for two-thirds of cases in the West Africa Ebola epidemic. Targeting these individuals could lead to better disease control measures in future outbreaks.
Researchers have identified a crucial mechanism by which the chikungunya virus infects host cells and mediates disease severity. This could present a future treatment target for both chikungunya and related viruses.
Researchers have demonstrated that a specific subclass of antibody is elevated in patients who develop severe secondary dengue; this could lead to better identification of those at risk and possibly improved treatments and vaccines.
Researchers have suggested that we are not doing enough to rectify shortcomings in the global response to disease outbreaks. In addition, they state that more progress must be made for the world to effectively cope with future pandemics.
In this review the author looks at the progress of vaccine development towards mosquito-borne viral diseases, such as Zika and chikungunya.