Researchers have identified the mTOR pathway as a ‘druggable’ key regulator of HIV-1 persister reservoirs in gut-homing CD4+ T cells.
Data from Population-based HIV Impact Assessments in five African countries have demonstrated promising progress towards controlling the HIV epidemic by 2020, however, they have also highlighted gaps.
New research displays how intestinal microbiota could regulate body composition; providing an insight into the molecular link between gut microbiota and the circadian clock via transcription factor NFIL3.
Researchers have pinpointed the four key pathogens responsible for diarrheal disease, a number one cause of morbidity among young children in sub-Saharan Africa and South Asia, highlighting the possible interventions available.
Novel drug, AQ-13, has demonstrated promise against uncomplicated malaria in a Phase II non-inferiority trial, presenting a potential new tool for tackling drug-resistant strains.
New research has demonstrated that the extent of Leishmania infection cycles in line with host circadian rhythms, presenting an opportunity for new therapeutics and optimizing prevention methods.
New research has uncovered that a neuropathogenic virus exploits the neuronal granule system for the transport of viral genomic RNA in dendrites, resulting in reproduction of the virus and severe neurological disease.
Researchers have successfully identified the key climatic parameters for predicting dengue virus outbreaks by tracking disease progression through the different climatic zones of India.