Rabies elimination is achievable and cost-effective, but decades of research have failed to translate into multi-national efforts in the worst-affected areas. So why is the ancient rabies virus still terrorizing the lives of so many people across the globe?
Infectious diseases and population mobility are intimately linked from the perspectives of clinical practice to global health policy. Mobility bridges significant epidemiological differences in the classical determinants of health for all diseases. The new reality is that “surveillance, detection and response” activities in infectious diseases clinical care and public health are the responsibility all members of society.
Take a look at how advancements in genetic engineering has led to advances in vaccine manufacturing, with a divergence from live cell cultures to recombinant production in host cells.
Horizontal gene transfer plagues the control of multi-drug resistant infections, but how exactly are genes transferred and can we stop them? In a recent Cell paper, Rubio-Cosials and colleagues detail the biochemical events leading up to the transfer of transposons carrying antibiotic resistance genes.
TB and HIV are two intertwined infective challenges for global health and therefore they need to be addressed with an integrated approach.
Rapid detection and identification of pathogens is crucial to combat biothreat agents. Here, we take a look at some of the emerging technologies and how they could be used to diagnose disease for civilian biodefense.
We take a look at the key microbiome therapeutics currently in the clinical pipeline for recurrent C. difficile infections and their prospects for the treatment of this disease in the future.
In the era of meta-omics, infection control and prevention must consider healthcare-associated infections in the global context of pathobiome.
In a recent study published in Nature Communications, researchers validated a novel screening approach to identify host-directed compounds that reduce the replication of intracellular pathogens, Julie Kaiser explains.
Biothreats are in the limelight of the current military, scientific and medical debate. Although it is arguable whether they are a major impending risk, their political and societal relevance is out of discussion. They are one of the collective fears which characterize our epoch.