Microbial domain biological resource centers that provide researchers with access to living cultures of microorganisms have adopted a code of conduct and best practice to prevent the misappropriation and misuse of microorganisms.
In a recent study published in Nature Communications, researchers demonstrated that acquired resistance to the polymixin antibiotic, colistin, can be detrimental to bacterial survival, revealing unique evolutionary trade-offs of this new form of resistance.
To round up 2017, we asked our Expert panel to choose their top papers from the year. Here, you can discover these articles and the reasons why they were chosen.
Researchers have demonstrated that antibiotic-resistance plasmids persist in the absence of antibiotics, provided that the efficiency of plasmid transfer exceeds a critical threshold, highlighting the limitations of ‘resistance-reversal’ strategies.
To date there have only been a handful of Phase III efficacy trials for HIV vaccine candidates, which have had varied, and in some cases controversial, results. Here we review the history of HIV vaccine efficacy studies and look into the vaccine candidates closest to front-line use.
In this piece, the authors give an overview of anti-virulence drugs, designed to selectively target key virulence factors of pathogenic bacteria, and one strategy for new antimicrobials.