Despite significant advances in the treatment of human immunodeficiency virus (HIV), there remain challenges. This review highlights recent advances in the application of nanotechnology to drug delivery, specifically with the purpose of improving HIV therapy.
Browsing: Basic > Drug Development
MedChemNet and Infectious Diseases Hub recently attended the first two days of the 19th RSC / SCI Medicinal Chemistry Symposium. Here, you can catch up on the session delving into drug discovery for the neglected tropical diseases.
Ahead of the Call to Action on Antimicrobial Resistance in Berlin the UK’s Chief Medical Officer, Sally Davies, spoke about the need to ensure antimicrobial resistance stays on the political agenda, and the role of the individual in achieving this, at Antibiotic Research UK’s annual lecture.
Silver nanoparticles have long been used as potent antibacterial agents. However, toxicity concerns of silver nanoparticles have limited their successful clinical applications. This research reports a simple and cost-effective method for the synthesis of nickel-prussian blue@silver nanocomposites.
Researchers have uncovered the pharmacodynamic properties of novel antifungal, F901318, taking it one step closer to testing in clinical trials
Researchers have developed a novel compound, L-HIPPO, which can prevent viral budding in HIV-infected cells. It has been suggested this compound could supplement existing ‘kick and kill’ strategies, allowing complete eradication of HIV in the body.
Researchers have designed potent peptide fusion inhibitors that can neutralize a broad range of influenza viruses and could present a promising avenue for future therapeutics.
Editor, Martha Powell, discusses the issues around the current guidance for treating HAT and gives an overview of the current clinical pipeline being spearheaded by the Drugs for Neglected Diseases initiative.
In this exclusive piece, the authors look at antihelmintics in both animal and human health – arguing that evolution of resistance necessitates drug development.