Browsing: Basic > Drug Development
In this podcast Dr Elizabeth Whittaker, Dr James Seddon, Dr Pete Dodd and Professor Beate Kampmann discuss their work in pediatric tuberculosis focusing on the areas of immunology, modelling and drug resistance.
Take a look at our new infographic, developed for World Tuberculosis Day, which explores the facts about current TB burden, the issues around drug resistance, and research and development moving forwards.
In this original research article, the authors determine the structural contributions of a compound set containing inhibitors of bacterial enzyme FabI.
Mark Blaskovich, Principal Investigator and Program Coordinator for the Community for Open Antimicrobial Drug Discovery (CO-ADD) discusses his work towards uncovering compounds with antibiotic potential and shares his thoughts on the best strategies to tackle antibiotic resistance moving forwards.
Researchers from Durham University have developed a new, simplified production process for a drug vital to treating cryptococcal meningitis; they hope this will reduce the drug’s cost and increase its availability in developing countries.
Researchers have discovered a novel regulator of the innate immune response that may lead to the development of new antivirals and vaccines.
Researchers have uncovered the role of inflammasome activation in leishmaniasis progression and severity, demonstrating that inhibiting these pathways may present a potential avenue for future treatments.
The WHO has published a report this week listing 12 families of antibiotic-resistant bacteria that are thought to pose the greatest public health risk and should be the focus for new treatments.