A team from Tel Aviv University have developed hybrid bacteriophage particles that may allow DNA transduction to new bacteria, expanding the range of currently used phages.
Browsing: Basic > Genetics / Genomics
Researchers have discovered sequence-specific interactions between hepatitis B proteins and pre-genome RNA that may play a crucial role in nucleocapsid assembly. This could be targeted in future drug development.
A novel platform has demonstrated an ability to simultaneously detect multiple pathogens in human blood samples, potentially leading to the development of multiple-assay devices for clinical use.
Researchers have examined the complex interaction between environmental pressures and human virulence in Cryptococcus neoformans, demonstrating some variants associated with clinical isolates.
A new assay has been developed for the faster, cheaper and less labour-intensive detection of replicating latent HIV in infected individuals.
Researchers have discovered a variation in the human red blood cell receptor glycophorin that appears to reduce the risk of severe malaria by 40%.
In this preliminary communication, the authors selected and characterized aptamers targeting the 5′-UTR from dengue virus, a sequence with important regulatory elements for its life cycle, with applications as potential antiviral and diagnostic tools.
Genotyping hepatitis C patients with advanced cirrhosis could help predict improvement after treatment, according to research presented at Digestive Disease Week®.
Prions are transmissible agents composed of aggregates of misfolded cellular prion protein (PrP) that cause fatal neurodegenerative diseases. Here the authors looks into what genomics can tell us about prion diseases, and gives a perspective on future needs.