0 Hybrid phage particles could increase bacterial host range
A team from Tel Aviv University have developed hybrid bacteriophage particles that may allow DNA transduction to new bacteria, expanding the range of currently used phages.
Browsing: Basic > Genetics / Genomics
0 Hepatitis B pre-genome RNA may promote nucleocapsid assembly
Researchers have discovered sequence-specific interactions between hepatitis B proteins and pre-genome RNA that may play a crucial role in nucleocapsid assembly. This could be targeted in future drug development.
0 New technology screens for multiple blood-borne pathogens simultaneously
A novel platform has demonstrated an ability to simultaneously detect multiple pathogens in human blood samples, potentially leading to the development of multiple-assay devices for clinical use.
0 Study examines population genomics in Cryptococcus neoformans
Researchers have examined the complex interaction between environmental pressures and human virulence in Cryptococcus neoformans, demonstrating some variants associated with clinical isolates.
0 New assay could detect hidden viral reservoirs in HIV-infected patients
A new assay has been developed for the faster, cheaper and less labour-intensive detection of replicating latent HIV in infected individuals.
0 Variation in red blood cell receptors may confer malaria resistance
Researchers have discovered a variation in the human red blood cell receptor glycophorin that appears to reduce the risk of severe malaria by 40%.
0 Characterization of oligonucleotide aptamers targeting the 5′-UTR from dengue virus
In this preliminary communication, the authors selected and characterized aptamers targeting the 5′-UTR from dengue virus, a sequence with important regulatory elements for its life cycle, with applications as potential antiviral and diagnostic tools.
0 PCR-based test developed for diagnosing sepsis
A novel diagnostic test has been developed for sepsis. The TaqMan-Based Multiplex real-time PCR detection system has shown promising results in new assessments.
0 Genetic polymorphisms could help to determine outcomes in hepatitis C cirrhosis patients
Genotyping hepatitis C patients with advanced cirrhosis could help predict improvement after treatment, according to research presented at Digestive Disease Week®.
0 “What’s next for genomics and prion diseases?”
Prions are transmissible agents composed of aggregates of misfolded cellular prion protein (PrP) that cause fatal neurodegenerative diseases. Here the authors looks into what genomics can tell us about prion diseases, and gives a perspective on future needs.