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Gene atlas of malaria parasite reveals potential drug and vaccine targets
Scientists from Imperial College London (UK) and the Wellcome Sanger Institute (Cambridge, UK) have mapped the genetic changes malaria parasites…
Browsing: Basic > Genetics / Genomics
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New sequencing studies shed more light on the B.1.1.7 SARS-CoV-2 variant
Two new studies have shed light on the B.1.1.7 variant, suggesting that while it is more transmissible, it does not…
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The genetic basis for a high level in clinical variability among COVID-19 patients – an interview with Alessandra Renieri
In this interview with Alessandra Renieri we hear about the GEN-COVID network in Italy working to dsicover the genetic variability in COVID-19 patients who show phenotypic differences and what this means for treating the disease.
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Malaria parasites resistant to artemisinin now prevalent in Africa
Malara parasites showing artemisinin resistance previously seen in South-East Asia have recently emerged in areas of Rwanda in Sub-Saharan Africa. If the mutation causing resistance becomes prevalent across the continent it could have major public health impacts.
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Is the new strain of SARS-CoV-2 more infectious than the last?
Researchers have identified a specific change in the SARS-CoV-2 coronavirus spike protein that may increase its transmission, making it more infectious in cell culture.
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COVID-19 research round-up: June
This month’s top COVID-19 research articles include several studies citing the benefits of facemasks, as well as research investigating adaptive immunity to SARS-CoV-2 and a genome-wide study exploring COVID-19 severity.
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A peek behind the paper – Wenqing Jiang on the application of evolutionary theories to SARS-CoV-2
Take a peek behind the scenes of a recent article published by Future Virology, titled ‘Pros and cons of the application…
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Adaptive immune responses to SARS-CoV-2 differ with HLA genetic variation
Scientists have investigated the genetic variation in immunity against seven viruses including the SARS-COV-2. The results reveal some HLA variants that may provide the most effective immune response to the viruses.
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Researchers repurpose cancer immunotherapy tools for COVID-19 vaccine research
Researchers have repurposed cancer immunotherapy tools to identify regions of SARS-CoV-2 to target with a vaccine. They believe the use of this strategy could help develop a vaccine that provides long-term protection from COVID-19.
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Smoking linked to increased expression of SARS-CoV-2 receptor
Researchers have demonstrated that cigarette smoke causes an increased expression of Angiotensin Converting Enzyme 2 (ACE2), the SARS-CoV-2 receptor, in the lungs. This suggests that individuals who smoke could be more susceptible to severe SARS-CoV-2 infections.