A team from the University of California, San Diego have created a new CRISPR editing system that can effectively target antibiotic resistance genes. The system is based on a positive feedback loop and has numerous potential applications, such as treating chronic bacterial infections.
Browsing: Basic > Genetics / Genomics
Published in Nature, new research elucidates the mechanism behind malarial resistance to piperaquine and suggests how this knowledge could be used to combat its spread.
Scientists believe they have uncovered how Plasmodium falciparum jumped hosts 50,000 years ago; from gorillas to humans. The study demonstrates a novel understanding of how pathogens can jump between species.
A team from the Broad Institute at MIT and Harvard have designed a Cas13–CRISPR construct, termed CARVER, that can detect and kill viruses inside human cells. The flexible CARVER system could be used as a new tool in research and the clinic.
Researchers have developed a game theory approach and a machine learning algorithm to accurately identify antibiotic resistance genes in bacteria.
Take a look behind the scenes of a recent Future Virology editorial, entitled ‘The emerging field of endogenous retroviruses: understanding their physiological role and contribution to diseases’ as we ask author Enzo Tramontano (Università degli studi di Cagliari, Italy) about human endogenous retroviruses, whether they could be linked with disease and the future of this field.
Researchers at Dartmouth’s Geisel School of Medicine have found that hypoxic conditions are linked to a hypoxia-typic morphotype of the pathogen Aspergillus fumigatus. This morphotype worsens the diseases progression of invasive aspergillosis in a murine model.
New research has suggested that an inherited genetic trait appears to protect some individuals against MRSA infections.
Scientists investigating increased scarlet fever cases have identified that a new dominant linage of Strep A with increased toxin production has emerged.
In a new sequencing study, researchers discovered a transcriptional signature in B cells associated with protection from SIV or HIV infection.