All epidemically successful HIV groups started to spread in early 20th century, this perspective piece looks into the factors that enabled adaptation of SIV to be sexually transmitted among humans.
Browsing: Basic > Genetics / Genomics
Scientists have revealed proteins, termed RIFINs, expressed on the surface of infected erythrocytes that may help the malaria parasite to suppress the host immune response, leading to severe infection.
Researchers have demonstrated that antibiotic-resistance plasmids persist in the absence of antibiotics, provided that the efficiency of plasmid transfer exceeds a critical threshold, highlighting the limitations of ‘resistance-reversal’ strategies.
Scientists have revealed that a human protein – identified as YTHDF2 – could prevent cancer by restricting the human herpes virus 8, otherwise known as Kaposi’s sarcoma-associated herpesvirus.
Researchers have carried out the largest genetic study of Anopheles gambiae, discovering the spread of resistance and high genetic diversity.
Researchers have discovered endemic malaria infection in a geographically-restricted set of wild bonobos, including a possible new species of the parasite.
Scientists have explored how the viral genome affects the infectious potency of HIV; discovering that viruses have likely evolved to remove CG dinucleotides in order to avoid surveillance to mammalian defence mechanisms.
Researchers have unveiled novel pathways controlled by the multiple antibiotic resistance operon and identified new ways in which bacteria protect themselves against antibiotics.
Scientists have analyzed whole-genome sequence data from a UK public health surveillance study to reveal new understandings of the Salmonella epidemic in sub-Saharan Africa.