0 Imaging study reveals how malaria parasites bypass antimalarial drugs
Published in Nature, new research elucidates the mechanism behind malarial resistance to piperaquine and suggests how this knowledge could be used to combat its spread.
Browsing: Basic > Genetics / Genomics
1 Have scientists identified how P. falciparum jumped hosts 50,000 years ago?
Scientists believe they have uncovered how Plasmodium falciparum jumped hosts 50,000 years ago; from gorillas to humans. The study demonstrates a novel understanding of how pathogens can jump between species.
0 CARVER: CRISPR–Cas13 system kills viruses in human cells
A team from the Broad Institute at MIT and Harvard have designed a Cas13–CRISPR construct, termed CARVER, that can detect and kill viruses inside human cells. The flexible CARVER system could be used as a new tool in research and the clinic.
0 Could game theory be used to predict antibiotic resistance genes?
Researchers have developed a game theory approach and a machine learning algorithm to accurately identify antibiotic resistance genes in bacteria.
0 A peek behind the paper – Enzo Tramontano on the emerging field of endogenous retroviruses
Take a look behind the scenes of a recent Future Virology editorial, entitled ‘The emerging field of endogenous retroviruses: understanding their physiological role and contribution to diseases’ as we ask author Enzo Tramontano (Università degli studi di Cagliari, Italy) about human endogenous retroviruses, whether they could be linked with disease and the future of this field.
0 Fungal biofilm morphology impacts disease progression
Researchers at Dartmouth’s Geisel School of Medicine have found that hypoxic conditions are linked to a hypoxia-typic morphotype of the pathogen Aspergillus fumigatus. This morphotype worsens the diseases progression of invasive aspergillosis in a murine model.
0 Genetic variation protective against MRSA infection
New research has suggested that an inherited genetic trait appears to protect some individuals against MRSA infections.
0 Novel strain of toxin-producing Strep A identified in the UK
Scientists investigating increased scarlet fever cases have identified that a new dominant linage of Strep A with increased toxin production has emerged.
0 B cell gene signature associated with protection efficacy in HIV vaccines
In a new sequencing study, researchers discovered a transcriptional signature in B cells associated with protection from SIV or HIV infection.
0 The Malaria Cell Atlas provides insights into gene clusters and future treatments
Researchers recently profiled the single-cell transcriptomes of thousands of individual parasites to provide the first high-resolution atlas of malaria parasite gene expression across the lifecycle.
