A global genomic survey of Streptococcus pneumoniae has identified 621 strains across 50 countries and has highlighted how the bacteria can evolve in response to vaccination.
Browsing: Basic > Genetics / Genomics
In this interview we speak with Sarah Earle from the University of Oxford (UK) about her use of GWAS to understand more about Neisseria meningitidis and its transition from an asymptomatic commensal to an invasive pathogen.
A cohort of scientists from the Wellcome Sanger Institute, the University of Cambridge, the Peter Doherty Institute for Infection and Immunity and the University of Queensland have identified novel targets using DNA sequencing, bringing research one step closer to developing a universal vaccine against Group A Streptococcus.
In this interview we speak to Vineet Menachery about his recent talk at the Microbiology Society’s Annual Conference (8–11 April, Belfast, UK) suggesting that CoV emergence is more complicated than receptor binding alone.
Scientists have created the world’s first living organism that has a synthetic and altered genetic code, built on only 61 codons as opposed to 64.
Antibiotic tolerance significantly reduces antibiotic efficacy and contributes to treatment failure; targeting both antibiotic tolerance and antibiotic resistance is critical to develop new antimicrobial strategies that will successfully eradicate hard-to-treat infections.
Take a look behind the scenes of a recent Future Virology review, entitled: ‘Comparative host genomics: Has recent human evolution affected our immune defense against hepatitis C virus?’, as we ask the authors about the importance of the IFNL4 gene and the work that’s still to be done in the field.
The accurate diagnosis of schistosomiasis, in both the mammalian and snail intermediate hosts as well as the environment, is extremely important in proper control and elimination. Despite multiple efforts over last few decades, the search for cheap, sensitive diagnostics for schistosomiasis is ongoing.
Researchers have compiled the most comprehensive collection of human intestinal bacteria to date, isolating over 100 bacterial species from healthy individuals for the first time.
Take a look at this month’s industry headlines including an FDA approval for a vaccine protecting against six diseases, positive clinical trial results for bacteraemia and dengue vaccines and new funding for CRSIPR-based antimicrobials.