Novel research suggests that type III interferon-mediated signalling could play a major role in controlling live-attenuated yellow fever virus infection in mice.
In this interview, we speak to Cornelia Lass-Flörl from the Innsbruck Medical University (Austria) who has a special interest in the epidemiology, diagnosis, prevention and therapy of fungal infections.
The pathogenicity of T. marneffei depends on the ability of the fungus to survive the killing process and replicate inside the host macrophage cells. This paper summarizes factors relating to the stress responses that contribute to the intracellular survival of T. marneffei
New research in macaque models has suggested that prior dengue or yellow fever exposure has no significant effects on subsequent Zika infection in vivo, despite demonstrated enhancement in cell culture.
Researchers have demonstrated that the efficacy of phage therapy is dependent on synergy with the host’s immune system.
A child born with HIV has been found to suppress the infection without the reliance on conventional antiretroviral therapy; this may have future implications on the therapeutic approaches to HIV especially in infants.
A new test to detect Zika infection has been labelled the ‘best-to-date’ in differentiating Zika from related viruses, and could become a simple and low-cost solution for detecting the infection.
A newly identified genetic variation in the IFITM3 gene has been associated with the severity of influenza in US patients, and could have predictive value to identify high-risk individuals.
New research suggests that blood vessels are unable to clear infection due to the lack of ubiquitination that takes place in the endothelial cells.
Researchers have identified the primary enzymatic source of reactive oxygen species in humans, discovering that this enzyme exacerbates viral pathogenicity and suggesting that it could be an antiviral target.
