0 Phages and immunomodulation
This article discusses evidence for phage engagement in regulating immunity, shedding new light on the potential immunoregulatory activities of phages which constitute an abundant part of the microbiome.
Browsing: Basic > Immunology
0 Research suggests novel mechanism of superantigen-induced pathology
Researchers have identified a subpopulation of T cells as key cytokine producers in addition to proposing a novel mechanism of immunosuppression following superantigen exposure.
0 Interleukin-37: a new molecular target for host-directed therapy of tuberculosis
Improved therapeutic strategies are in urgent need for better control and eradication of tuberculosis. In this editorial, the authors evaluate interleukin-37 as a new molecular target for the therapy of tuberculosis.
0 ASM Microbe: NS1-based Zika vaccine demonstrates promise in mice
Research presented at ASM Microbe has reported a Zika vaccine based on the NS1 protein can induce protective immunity in mouse models after a single dose.
0 Could bioelectricity help regulate the innate immune system?
Researchers have discovered that compounds altering transmembrane potential in Xenopus laevis may improve resistance to E. coli infection.
0 IDHTalks with Helen McShane: Developing a new tuberculosis vaccine
Helen McShane discusses her work leading the TB vaccine research program at Oxford University, and shares her thoughts on the challenges facing vaccine development and eradication of this disease.
0 Malaria during pregnancy may alter babies’ risk of later infection
Study discovers that high levels of maternal microchimerism may directly affect the offspring’s immune system even after birth.
0 Targeting Epstein–Barr virus in multiple sclerosis – an interview with Michael Pender
Michael Pender discusses promising interim findings from a Phase 1 study investigating a novel treatment for multiple sclerosis based on the realtionship with Epstein–Barr virus.
0 Novel drug targets identified to fight off Chlamydia infections
Researchers have utilized CRISPR/Cas9 technology on human induced pluripotent stem cells to identify genes involved in fighting off Chlamydia trachomatis infections.
0 How can the gut microbiota affect immune recovery in HIV-infected individuals?
Given the ability of the microbiota to instruct the immune system and control the inflammatory response, the authors discuss the potential of targeting the microbiota to improve the immune recovery and dampen inflammation during HIV infection.