A new study has identified cyclin-dependent kinases as the key regulator of chromatin snares that are essential for neutrophil immune defense.
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Researchers from Yale University have suggested that the immune response may be responsible for neurological complications in Zika infection, as opposed to the virus itself.
Scientists have explored how the viral genome affects the infectious potency of HIV; discovering that viruses have likely evolved to remove CG dinucleotides in order to avoid surveillance to mammalian defence mechanisms.
Researchers have demonstrated that mice previously infected with dengue have protection against Zika virus that appears to be conferred by cytotoxic T cells.
Scientists discover a new powerful protective immune pathway triggered by ion channels in airway epithelial cells.
Researchers have uncovered five new targets for malaria vaccine development, suggesting that targeting multiple steps of erythrocyte invasion is more likely to produce an effective vaccine.
Researchers have discovered that antibodies taken from dengue virus infected individuals are effective in treating Zika infection – a closely related flavivirus – in rodents.
A novel trispecific antibody has been developed by researchers from the NIH and Sanofi, demonstrating effectiveness against of 99% of HIV strains and protective immunity in non-human primates.
Researchers have identified the mTOR pathway as a ‘druggable’ key regulator of HIV-1 persister reservoirs in gut-homing CD4+ T cells.