Browsing: Basic > Immunology
A novel trispecific antibody has been developed by researchers from the NIH and Sanofi, demonstrating effectiveness against of 99% of HIV strains and protective immunity in non-human primates.
Researchers have identified the mTOR pathway as a ‘druggable’ key regulator of HIV-1 persister reservoirs in gut-homing CD4+ T cells.
Maternal microchimerism (MMc) is a normal part of pregnancy, however, relatively little work has been done exploring the intersection of MMc and infectious disease. Here, Whitney Harrington discusses it’s implications in malaria.
Novel research suggests that type III interferon-mediated signalling could play a major role in controlling live-attenuated yellow fever virus infection in mice.
In this interview, we speak to Cornelia Lass-Flörl from the Innsbruck Medical University (Austria) who has a special interest in the epidemiology, diagnosis, prevention and therapy of fungal infections.
The pathogenicity of T. marneffei depends on the ability of the fungus to survive the killing process and replicate inside the host macrophage cells. This paper summarizes factors relating to the stress responses that contribute to the intracellular survival of T. marneffei
New research in macaque models has suggested that prior dengue or yellow fever exposure has no significant effects on subsequent Zika infection in vivo, despite demonstrated enhancement in cell culture.
Researchers have demonstrated that the efficacy of phage therapy is dependent on synergy with the host’s immune system.
A child born with HIV has been found to suppress the infection without the reliance on conventional antiretroviral therapy; this may have future implications on the therapeutic approaches to HIV especially in infants.