0 Tuberculosis: ‘Suicide’ toxin–antitoxin system identified as a drug target
Researchers have investigated a toxin–antitoxin system in tuberculosis as a therapeutic target, providing the first high-resolution details.
Browsing: Basic > Molecular biology
0 Vaccinia virus hijacks host cell motility to aid spread
New research has suggested that vaccinia viruses trick infected host cells into activating their cell movement mechanism, rapidly spreading the virus.
0 Recent advances and an update on gastrointestinal infections
Gauri Godbole, from Public Health England, gives us an overview of recent advances and updates in the field of gastrointestinal infections – from the impact of the microbiome to the growing threat of antimicrobial resistance.
1 Precision diagnostics: breakthrough test can screen all known bacterial infections simultaneously
Researchers from the Center for Infection and Immunity have made a major breakthrough in diagnoses of pathogenic bacteria with their design, the BacCapSeq platform. It’s the first precision medicine platform to allow simultaneous screening for all known bacterial pathogens, as well as markers for antibiotic resistance and virulence.
0 Ebola nucleocapsid modeled to near-atomic resolution
A team from the Okinawa Institute of Science and Technology Graduate University has used cryo-EM to model the nucleocapsid protein of Ebola virus, potentially uncovering novel drug targets.
0 Genomics in malaria – an interview with Dyann Wirth
Genomics is increasingly being adopted into both research and clinical settings. Here, we speak to Dyann Wirth about the use of genomics in the field of malaria, from what it can uncover about the parasite to the hurdles that need to be overcome moving towards elimination.
0 E. coli: A helpful bacterium?
A study by a team of researchers demonstrates that the commonly known food poisoning pathogen E.coli is integral in promoting health by producing a compound which helps cells absorb iron.
0 Nanoplasmonics used for monitoring biofilm formation
Researchers from the Okinawa Institute of Science and Technology have developed a method to study biofilm formation, and how it is affected by drugs, with high efficacy.
0 What determines Ebolavirus pathogenicity? – an interview with Mark Wass
At the recent Microbiology Society Annual Conference (10–12 April, Birmingham, UK) we spoke to Mark Wass about his work on Ebolaviruses in which he’s delved into the molecular determinants of the virus’s pathogenicity.
0 ECCMID18: Biomarker identified for P. aeruginosa could act as treatment target
A new gene identified in P. aeruginosa could act as a prognostic biomarker and treatment target for patients with bloodstream infections.
