This research, published in Future Microbiology, screens host proteins for those that interact with EspF via flow cytometry and high-throughput screening to try and shed light on how EspF affects host cells to induce colitis and even colorectal carcinogenesis.
Browsing: Basic > Molecular biology
Researchers have identified that the Ebola virus recruits a host enzyme, PP2A-B56, for replication, demonstrating that inhibiting this pathway could be a target for drug discovery.
Researchers have established a map of protein interactions for the replication machinery of chronic viruses, shedding insight into viral strategies and uncovering potential drug targets.
Scientists have revealed proteins, termed RIFINs, expressed on the surface of infected erythrocytes that may help the malaria parasite to suppress the host immune response, leading to severe infection.
In a recently published study, researchers have utilized spectroscopy techniques to provide an in-depth understanding of the atomic interaction that occurs when viral buds are released from the host cell’s membrane after infection.
Scientists have unveiled the molecular architecture of two key proteins required for bacillus cell wall elongation. Inhibiting their interaction could provide a new mode of action for antibiotics against highly resistant bacteria.
According to a recently published study, the effectiveness of the H3N2 vaccine could be attributed to the egg-based vaccine production process, which may ultimately render the vaccine to be less effective in humans.
Researchers have designed potent peptide fusion inhibitors that can neutralize a broad range of influenza viruses and could present a promising avenue for future therapeutics.
A recent study published in PLOS Pathogens has indicated that children with a lower diversity of microbes in their gut microbiome are more susceptible to severe infection by Entamoeba histolytica.