Horizontal gene transfer plagues the control of multi-drug resistant infections, but how exactly are genes transferred and can we stop them? In a recent Cell paper, Rubio-Cosials and colleagues detail the biochemical events leading up to the transfer of transposons carrying antibiotic resistance genes.
Browsing: Basic > Molecular biology
In this infographic we take a look at the diagnostics currently in the pipeline for tuberculosis, highlighting the stage of development and intended use.
A proof-of-concept study has demonstrated promise for a new vaccine production platform, which was used to build a prototype synthetic flu vaccine.
This research, published in Future Microbiology, screens host proteins for those that interact with EspF via flow cytometry and high-throughput screening to try and shed light on how EspF affects host cells to induce colitis and even colorectal carcinogenesis.
Researchers have identified that the Ebola virus recruits a host enzyme, PP2A-B56, for replication, demonstrating that inhibiting this pathway could be a target for drug discovery.
Researchers have established a map of protein interactions for the replication machinery of chronic viruses, shedding insight into viral strategies and uncovering potential drug targets.
Scientists have revealed proteins, termed RIFINs, expressed on the surface of infected erythrocytes that may help the malaria parasite to suppress the host immune response, leading to severe infection.
In a recently published study, researchers have utilized spectroscopy techniques to provide an in-depth understanding of the atomic interaction that occurs when viral buds are released from the host cell’s membrane after infection.
Scientists have unveiled the molecular architecture of two key proteins required for bacillus cell wall elongation. Inhibiting their interaction could provide a new mode of action for antibiotics against highly resistant bacteria.