0 Phages and immunomodulation
This article discusses evidence for phage engagement in regulating immunity, shedding new light on the potential immunoregulatory activities of phages which constitute an abundant part of the microbiome.
Browsing: Basic > Pathology & Pathogenesis
0 Research suggests novel mechanism of superantigen-induced pathology
Researchers have identified a subpopulation of T cells as key cytokine producers in addition to proposing a novel mechanism of immunosuppression following superantigen exposure.
0 Small-molecule antifungal compound identified for C. albicans
Researchers have reported a small-molecule inhibitor of Candida albican protein Bdf1 and demonstrated the compound yields decreased fungal viability, suggesting a possible future antifungal.
0 Could vitamin A levels affect tuberculosis risk?
Researchers have discovered that low levels of vitamin A are associated with a 10-fold increase in the risk of developing tuberculosis among household contacts of TB patients.
0 What impact does the sandfly nanobiome have on leishmaniasis development?
Martin Olivier, discusses how the nanobiome of vectors may impact the infectious processes of disease, highlighting his work on exosomes in sandflies and leishmaniasis.
0 Function of Ebola delta peptide uncovered
Researchers investigating Ebola virus have uncovered the function of delta protein, which is released in high levels during infection, and findings suggest it could play a crucial role in disease pathology.
0 New assay could detect hidden viral reservoirs in HIV-infected patients
A new assay has been developed for the faster, cheaper and less labour-intensive detection of replicating latent HIV in infected individuals.
0 Could targeting bacterial metabolism reduce treatment times for tuberculosis?
Researchers have uncovered metabolic changes in Mycobacterium tuberculosis, which may enable the bacteria to withstand exposure to antimicrobials, suggesting that targeting these pathways could reduce treatment times.
0 Identifying novel antiviral targets against enterovirus 71: where are we?
This review aims to provide a better understanding of HEV71 virology and potential antivirals for progressive clinical development with respect to their elucidated mechanistic actions.
0 New treatment approach for influenza targets host-cell metabolism
Researchers have discovered that investigational cancer drug, BEZ235, may reduce the severity of influenza infection by altering host-cell metabolism, representing new treatment avenues.