0 Novel antibiotic resistance genes discovered
Researchers have uncovered novel bacterial genes conferring B1 metallo-β-lactamases, and therefore resistance to last-resort antibiotics the carbapenems.
Browsing: Basic > Pathology & Pathogenesis
0 Interspecies transmission of influenza: straight from the horse’s mouth
In our latest piece, Janet Daly discusses the species jump of influenza A virus from horses to dogs and the insights this gives into the factors involved in interspecies transmission events.
0 Inkoo virus – a common but unrecognized mosquito-borne virus in northern Europe
Magnus Evander gives past, present and future perspectives on Inkoo virus – a mosquito-borne virus in northern Europe causing fever and meningoencephalitis.
0 Conference report – British Society for Parasitology Autumn Symposium
Missed out on attending the British Society for Parasitology’s Autumn Symposium? Read our report of the event here, including talks from Roy Anderson and David Molyneux.
0 Novel ‘lock-in and apoptosis’ strategy could help eliminate HIV reservoirs
Researchers have developed a novel compound, L-HIPPO, which can prevent viral budding in HIV-infected cells. It has been suggested this compound could supplement existing ‘kick and kill’ strategies, allowing complete eradication of HIV in the body.
0 Staphylococcus epidermidis: a major player in bacterial sepsis?
Blood infection (sepsis) causes millions of deaths worldwide and is the most frequent cause of death in hospitalized patients. Sepsis…
0 Research sheds new light on Ebola pathogenesis
A new study has identified the role of T cell protein, Tim-1, in initiating the inflammatory response that is central to Ebola pathogenesis and disease severity.
0 From wildlife to humans with the PREDICT project – an interview with Tracey Goldstein
In this interview, we speak to Tracey Goldstein, Co-Principal Investigator and Pathogen Diagnostics Co-Lead for the viral emergence early-warning project PREDICT, who gives us an overview of the project, what brought it about and some of the findings thus far.
0 Intercellular peptide identified as a potential therapeutic target in group A Streptococcus
Researchers have discovered that a leaderless intercellular peptide signal may contribute to group A Streptococcus virulence; providing a framework for the identification in other microorganisms that may potentially serve as therapeutic targets.
0 New drug target against HIV permissiveness in CD4+ T cells
Researchers have identified the mTOR pathway as a ‘druggable’ key regulator of HIV-1 persister reservoirs in gut-homing CD4+ T cells.