CRISPR/Cas9 has been demonstrated to excise HIV-1 DNA from host tissues in vivo according to new research; this marks a major step towards a permanent cure for HIV infection.
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In this exclusive opinion piece, the authors discuss how a neuroattenuated varicella zoster virus (VZV) vaccine could provide promising protection against VZV infection.
Researchers have utilized CRISPR/Cas9 technology on human induced pluripotent stem cells to identify genes involved in fighting off Chlamydia trachomatis infections.
Given the ability of the microbiota to instruct the immune system and control the inflammatory response, the authors discuss the potential of targeting the microbiota to improve the immune recovery and dampen inflammation during HIV infection.
In this editorial the authors discuss how targeting the human TREX complex could prevent herpesvirus replication, highlighting their own work targeting herpesvirus lytic replication through inhibition of the hTREX complex.
Although understanding of Ebola virus pathogenesis has rapidly increased recently, many questions relating to the role of the vascular system remain unanswered. The authors here discuss how Ebola virus infection can cause endothelial dysfunction and coagulopathy.
Two proteins, crucial for enabling the cell traversal activity of malarial parasites, have been identified by a team of researchers who hope these could be targeted in drug or vaccine development.
This opinion piece discusses the many challenges inherent in caring for HIV+ individuals with new-onset seizure. With more questions than answers in both resource-limited settings and more developed medical environments what do we need to elucidate going forwards?