Researchers have uncovered metabolic changes in Mycobacterium tuberculosis, which may enable the bacteria to withstand exposure to antimicrobials, suggesting that targeting these pathways could reduce treatment times.
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This review aims to provide a better understanding of HEV71 virology and potential antivirals for progressive clinical development with respect to their elucidated mechanistic actions.
Researchers have discovered that investigational cancer drug, BEZ235, may reduce the severity of influenza infection by altering host-cell metabolism, representing new treatment avenues.
Researchers have discovered a variation in the human red blood cell receptor glycophorin that appears to reduce the risk of severe malaria by 40%.
In this preliminary communication, the authors selected and characterized aptamers targeting the 5′-UTR from dengue virus, a sequence with important regulatory elements for its life cycle, with applications as potential antiviral and diagnostic tools.
In this interview, Joop Arends discusses his thoughts on the future of diagnosis and management of hepatitis C, and also gives us his highlights from ECCMID.
Prions are transmissible agents composed of aggregates of misfolded cellular prion protein (PrP) that cause fatal neurodegenerative diseases. Here the authors looks into what genomics can tell us about prion diseases, and gives a perspective on future needs.
In line with Hepatitis Awareness Month, we spoke to Marcus Dorner about his current research into the host–virus interactions in hepatitis B and C infection, their implications for vaccine development and more.