Elucidating the effects of virus infections on the biological activity of stem cells may help improve the safety and efficacy of clinical stem cell transplantations. This study explores the underlying influence of HSV type-1 (HSV-1) infection on the energy metabolism of human umbilical cord-derived mesenchymal stem cells (UCMSCs).
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Data from Population-based HIV Impact Assessments in five African countries have demonstrated promising progress towards controlling the HIV epidemic by 2020, however, they have also highlighted gaps.
In this exclusive piece, the authors look at antihelmintics in both animal and human health – arguing that evolution of resistance necessitates drug development.
In this review, the authors consider phage therapy that can be used for treating bacterial infections in humans, domestic animals and even biocontrol in foods. They also explore common practice – both experimental and, in certain regions of the world, clinical – of mixing therapeutic phages into cocktails consisting of multiple virus types.
Researchers have pinpointed the four key pathogens responsible for diarrheal disease, a number one cause of morbidity among young children in sub-Saharan Africa and South Asia, highlighting the possible interventions available.
Novel drug, AQ-13, has demonstrated promise against uncomplicated malaria in a Phase II non-inferiority trial, presenting a potential new tool for tackling drug-resistant strains.
Evidence has emerged suggesting a link between certain hormonal contraceptives and HIV acquisition risk. This article reviews the epidemiologic studies and potential biologic mechanisms evaluating the association between hormonal contraceptive methods and HIV risk.
More than a century after its description and the discovery of the bacterial etiological agent, and despite its major burden globally, leptospirosis remains largely under-recognized.