When investigating the effect tolerance to a single drug has when combination therapy is being used to prevent antibiotic resistance, a team of researchers demonstrated that antimicrobial tolerance can promote resistance.
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A team from the University of California, San Diego have created a new CRISPR editing system that can effectively target antibiotic resistance genes. The system is based on a positive feedback loop and has numerous potential applications, such as treating chronic bacterial infections.
The CDC has released an updated report outlining the burden of antimicrobial resistance in the USA and the greatest threats that face this country.
In this interview we speak to Keith Kaye, from the University of Michigan (MI, USA) about the RESTORE-IMI 2 study, its results and why ICU patients represent an unmet need.
Bacteriophage have been touted as the solution for antibiotic resistant microbes, why are they not being used in mainstream medicine?
Researchers have developed a game theory approach and a machine learning algorithm to accurately identify antibiotic resistance genes in bacteria.
Panel discussion now available on demand. In this panel discussion marking World Antibiotic Awareness Week our experts will provide insights on the key topics in the current debate around antimicrobial resistance – from bench to bedside – including stewardship, drug and treatment development, resistance mechanisms and a ‘One Health’ approach.
Research has suggested that prophylactic antibiotics are overprescribed before dental visits, and that taking them could actually increase the likelihood of adverse effects.