We speak to infectious diseases specialist, Ellie Goldstein (Santa Monica, CA, USA), about his recent publication on real world data and the challenges facing drug-resistant infections.
Browsing: Clinical > Antimicrobial Resistance
Changes in both antibiotic concentration and nutrient availability can push populations beyond a tipping point, creating irreversible shifts in community composition to drug-resistance.
Small-molecule compounds designed to tag the cell surface of Gram-negative bacteria and trigger an immunological response have shown promise.
Antibiotic effectiveness can be restored if utilized in the correct combination with each other, non-antibiotic adjuvants or even food additives.
The US FDA has approved Zemdri for use in adults with complicated urinary tract infections; however, the agency has also issued a response for bloodstream infections noting there isn’t substantial evidence of Zemdri’s effectiveness.
Researchers have discovered a high prevalence of colistin-resistant E. coli in the Vietnamese town of Nguyen Xa, according to research presented at ASM Microbe.
An isolate of colistin-heteroresistant, carbapenem-resistant, hypervirulent/hypermucoviscous Klebsiella pneumoniae has been identified in the USA.
In research presented at ASM Microbe a team have delved into the dynamics of E. coli in urban streams in the USA, indicating possible antibiotic resistance activity.
A study presented at ASCO this weekend has suggested that antibiotic use greatly reduces the progression-free survival and overall survival of cancer patients receiving immunotherapy.