ECCMID 2019 saw the first presentation of the results from ASPECT-NP, a randomized, multi-center Phase III trial evaluating Merck’s ZERBAXA® (ceftolozane–tazobactam) for the treatment of patients with ventilated nosocomial pneumonia. In light of this we spoke to investigators Marin Kollef and Ignacio Martin-Loeches about the rationale behind this trial, its design and the key findings.
Browsing: Clinical > Antimicrobial Resistance
Phage therapy using genetically engineered bacteriophages has treated a 15-year-old girl who developed a drug-resistant infection following a lung transplant, as outlined in Nature Medicine.
Antibiotic tolerance significantly reduces antibiotic efficacy and contributes to treatment failure; targeting both antibiotic tolerance and antibiotic resistance is critical to develop new antimicrobial strategies that will successfully eradicate hard-to-treat infections.
New research has suggested that a combination treatment of gentamicin with azithromycin was almost as effective as the currently used ceftriaxone for treating genital gonorrhea.
International organizations have united on critical recommendations to combat antimicrobial resistance in a ground-breaking report released today.
Staying in a hotel or private accommodation has been associated with carrying ESBL-producing bacteria in travelers to low- and middle-income countries, according to research presented at ECCMID.
New research presented at ECCMID has identified a novel association between antimicrobial resistance and climatic factors in Europe.
Only one-third of patients entering the emergency department with a suspected UTIs actually have evidence of infection, however, almost all were treated with antibiotics, according to research presented at ECCMID.
Contamination of privacy curtains with multidrug-resistant organisms could be a common issue and a source of transmission to patients, according to research presented at ECCMID.