Research has suggested that prophylactic antibiotics are overprescribed before dental visits, and that taking them could actually increase the likelihood of adverse effects.
Browsing: Clinical > Antimicrobial Resistance
Research from IDWeek has suggested that conventionally raised poultry is twice as likely to contain multidrug-resistant Salmonella when compared with poultry labelled antibiotic-free or organic.
Researchers have observed a bacterial mechanism that allows bacteria to change form and resist antibiotics, without the transfer of resistance genes.
Take a look at this month’s industry headlines including FDA warnings over hepatitis C drugs in patients with liver injury, a new infectious diseases strategy for the UK and priority review for Merck’s Ebola vaccine.
In this perspective piece for Future Microbiology the authors argue that there is a lack of innovation to meet the current shortcomings of antibiotic R&D.
Researchers have discovered that a relatively ancient drug efflux pump from Haemophilus influenzae exports the same antibiotics as its evolved counterpart from Escherichia coli, but was mitigated by a leaky porin channel.
Take a look behind the scenes of a recent Future Microbiology review, entitled ‘An update on drug repurposing: Is it useful for tacking antimicrobial resistance?’ as we ask the authors about what challenges and limitations drug repurposing faces, in addition to why this strategy could be a promising alternative to the traditional drug discovery pipeline.
Xenleta™ (lefamulin), developed by Nabriva Therapeutics, has been approved by the US FDA for adults with community-acquired bacterial pneumonia, marking the first new antibiotic with a novel mechanism of action to be approved in nearly two decades.
The US FDA has approved Pretomanid tablets in combination with bedaquiline and linezolid for the treatment of specific types of drug-resistant pulmonary tuberculosis.
Multidrug resistance to two antimalarials, used in combination as a first-line therapy, has been found using genomic surveillance to be rapidly spreading throughout Asia.