In this original research article, the authors determine the structural contributions of a compound set containing inhibitors of bacterial enzyme FabI.
Browsing: Clinical > Antimicrobial Resistance
With TB still presenting a major health problem across the globe, we spoke to Timothy Rodwell about the challenges currently facing TB diagnostics and his work as acting head of the TB Program at FIND.
In this interview to mark World TB Day Madhukar Pai discusses the challenges surrounding TB case detection and the future of TB diagnostics.
Study demonstrates the value of phage therapy in effectively treating Pseudomonas aeruginosa infections.
Mark Blaskovich, Principal Investigator and Program Coordinator for the Community for Open Antimicrobial Drug Discovery (CO-ADD) discusses his work towards uncovering compounds with antibiotic potential and shares his thoughts on the best strategies to tackle antibiotic resistance moving forwards.
The WHO has published a report this week listing 12 families of antibiotic-resistant bacteria that are thought to pose the greatest public health risk and should be the focus for new treatments.
Could nanoconstructs be utilized to fight infection? This Editorial discusses the potential of photoactivatable nanodrugs to overcome the growing problem of acquired antibiotic resistance in bacteria as well as the intrinsic resistance of biofilm-associated infections.
Rapid diagnostic tests for detecting emerging antibiotic resistance are mostly available and should be used now state authors Patrice Nordmann and Laurent Poirel (University of Fribourg, Switzerland). This exclusive opinion piece discusses available diagnostics and why we should take action.
In this study the authors delve into fighting antibiotic resistance, aiming to synthesize and evaluate the antimicrobial activity of a new series of quinazolinone azolyl ethanols .
This perspective discusses the urgent need for novel and efficient antimicrobial strategies against C. difficile and the authors evaluate the application of the acyldepsipeptides family of antibiotics to treat C. difficile infections.