A team of researchers have demonstrated the transmission of a single bacterial strain that possessed a carbapenem-resistance gene, using whole-genome sequencing.
Browsing: Clinical > Antimicrobial Resistance
An in vitro study has identified potent antibiotic properties possessed by cannabidiol, discovering activity against Gram-positive bacteria such as Staphylococcus aureus and Streptococcus pneumoniae.
New research, presented at ASM Microbe (20—24 June 2019, San Francisco, CA, USA), has suggested that public campaigns have largely been ineffective at reducing antibiotic prescribing.
Researchers have shown that plant-foods, not just meats, can contribute to the transmission of antibiotic resistance to the gut microbiome.
Scientists at California State University, Fresno have identified multidrug resistance in six probiotic Bacillus strains to several antibiotics through genetic analysis.
ECCMID 2019 saw the first presentation of the results from ASPECT-NP, a randomized, multi-center Phase III trial evaluating Merck’s ZERBAXA® (ceftolozane–tazobactam) for the treatment of patients with ventilated nosocomial pneumonia. In light of this we spoke to investigators Marin Kollef and Ignacio Martin-Loeches about the rationale behind this trial, its design and the key findings.
Phage therapy using genetically engineered bacteriophages has treated a 15-year-old girl who developed a drug-resistant infection following a lung transplant, as outlined in Nature Medicine.
Antibiotic tolerance significantly reduces antibiotic efficacy and contributes to treatment failure; targeting both antibiotic tolerance and antibiotic resistance is critical to develop new antimicrobial strategies that will successfully eradicate hard-to-treat infections.
New research has suggested that a combination treatment of gentamicin with azithromycin was almost as effective as the currently used ceftriaxone for treating genital gonorrhea.