Despite challenges and setbacks in the decades-long struggle to eradicate polio, effective vaccines, evidence-based policy and global cooperation have brought the world closer to achieving polio eradication than ever before.
Browsing: Clinical > Vaccines
In new research, the first live-attenuated Zika vaccine has been demonstrated to protected mice against the virus after a single dose.
Oral delivery of vaccines is an attractive approach but is hampered by a number of challenges. Here, the authors discuss the need to include immunostimulatory adjuvants in oral vaccines to overcome oral tolerance and elicit effector immune responses locally within the intestine.
New research suggests that maternal vaccination may be the most effective strategy for preventing pertussis in infants throughout the first year of life.
Take a look at our new infographic, developed for World Tuberculosis Day, which explores the facts about current TB burden, the issues around drug resistance, and research and development moving forwards.
A new mathematical model suggests that the development of a vaccine against HIV, even if it is only partially effective, could be hugely important for the elimination of HIV worldwide.
A Phase I clinical trial has demonstrated two investigational Ebola vaccines generate a durable immune response 1 year after vaccination.
Despite an urgent need for a universal flu vaccine there is no such vaccine in the market and no regulatory guideline for its approval. This special report from Future Virology proposes a stepwise process for regulatory and marketing approval for such a vaccine and discusses the epitope-based vaccine candidate Multimeric-001 (M-001).
The first study to investigate attitudes to the child flu vaccine in the UK has reported that concerns around the vaccines safety, efficiency and side effects may be reducing uptake.
We at Infectious Diseases Hub recently spoke to Peter Openshaw, Professor of Experimental Medicine at Imperial College London (UK), about his research into respiratory viruses and the challenges currently facing science policy and funding.