Despite significant advances in the treatment of human immunodeficiency virus (HIV), there remain challenges. This review highlights recent advances in the application of nanotechnology to drug delivery, specifically with the purpose of improving HIV therapy.
Silver nanoparticles have long been used as potent antibacterial agents. However, toxicity concerns of silver nanoparticles have limited their successful clinical applications. This research reports a simple and cost-effective method for the synthesis of nickel-prussian blue@silver nanocomposites.
In this editorial the authors discuss the current methods for identifying carbapenemase producers and give a future perspective, highlighting the imemdiate action required to tackle the broader problem of antimicrobial resistance.
This report reviews the use of recombinase polymerase amplification for virus detection, showing that the method has favorable fundamental properties supporting its promise for rapid point-of-care detection of enteric viruses.
While sepsis is well defined clinically, the molecular immunological mechanisms that underlie the development of sepsis are poorly understood.
Elucidating the effects of virus infections on the biological activity of stem cells may help improve the safety and efficacy of clinical stem cell transplantations. This study explores the underlying influence of HSV type-1 (HSV-1) infection on the energy metabolism of human umbilical cord-derived mesenchymal stem cells (UCMSCs).
In this review, the authors consider phage therapy that can be used for treating bacterial infections in humans, domestic animals and even biocontrol in foods. They also explore common practice – both experimental and, in certain regions of the world, clinical – of mixing therapeutic phages into cocktails consisting of multiple virus types.
During infection development in the host, Paracoccidioides spp. faces the deprivation of micronutrients, this induces the remodeling of proteins present in different metabolic pathways. This study attempts to identify membrane proteins and their regulation by zinc in Paracoccidioides lutzii.
Evidence has emerged suggesting a link between certain hormonal contraceptives and HIV acquisition risk. This article reviews the epidemiologic studies and potential biologic mechanisms evaluating the association between hormonal contraceptive methods and HIV risk.
In this forward-looking perspective piece, the author examines the emerging virus, Nipah and options for its prevention and treatment.