A Phase I clinical trial has demonstrated that microneedle patches for flu vaccinations are safe, well-tolerated, immunogenic and also preferred by participants over intramuscular injection.
Researchers have discovered that cell division sites in mycobacteria are correlated with inherited wave-like morphological landmarks on the cell surface.
A new study has investigated the effects of commonly used topical antimicrobials on the skin microbiome, discovering that antibiotics have a major and long-lasting effect.
A team from Tel Aviv University have developed hybrid bacteriophage particles that may allow DNA transduction to new bacteria, expanding the range of currently used phages.
Researchers have identified a subpopulation of T cells as key cytokine producers in addition to proposing a novel mechanism of immunosuppression following superantigen exposure.
Researchers have discovered sequence-specific interactions between hepatitis B proteins and pre-genome RNA that may play a crucial role in nucleocapsid assembly. This could be targeted in future drug development.
A live-attenuated Ebola vaccine has demonstrated promising results in a Phase I randomized controlled trial assessing safety and immunogenicity, according to a Canadian study.
Researchers have reported a small-molecule inhibitor of Candida albican protein Bdf1 and demonstrated the compound yields decreased fungal viability, suggesting a possible future antifungal.
A novel platform has demonstrated an ability to simultaneously detect multiple pathogens in human blood samples, potentially leading to the development of multiple-assay devices for clinical use.
Researchers have examined the complex interaction between environmental pressures and human virulence in Cryptococcus neoformans, demonstrating some variants associated with clinical isolates.