New research links clusters of virulence-associated pir genes in malaria parasites with their ability to persist in the body, sustaining transmission once symptoms have subsided.
Researchers have pioneered an mRNA-based vaccine against Zika that has demonstrated promising results in pre-clinical trials on mice and monkeys.
Researchers have identified a crucial mechanism by which the chikungunya virus infects host cells and mediates disease severity. This could present a future treatment target for both chikungunya and related viruses.
Researchers have demonstrated that a specific subclass of antibody is elevated in patients who develop severe secondary dengue; this could lead to better identification of those at risk and possibly improved treatments and vaccines.
Researchers have suggested that we are not doing enough to rectify shortcomings in the global response to disease outbreaks. In addition, they state that more progress must be made for the world to effectively cope with future pandemics.
Researchers have discovered that a component of the Staphylococcus aureus cell wall appears to be responsible for elevated virulence in community-associated MRSA infections. This mechanism could present a target for novel anti-infective strategies.