Hold the antibiotics: next-generation hydrogels have arrived
Scientists in Sweden have created a new class of non-antibiotic hydrogel capable of fighting multidrug-resistant…
Browsing: Antibiotics
Bacteriophage ‘Muddy’ buddies up with antibiotic to combat antibiotic resistance
Researchers discover bacteriophage ‘Muddy’ and antibiotic rifabutin as a new dynamic duo combination therapy against antibiotic-resistant Mycobacterium abscessus infection in a cystic fibrosis zebrafish…
Resistance-free ‘poisoned arrow’ antibiotic kills Gram-negative bacteria
Researchers from Princeton University have uncovered an antibiotic molecule capable of killing both Gram-negative and Gram-positive bacteria using two simultaneous mechanisms, while also avoiding antibiotic resistance.
2020: A molecular odyssey – could artificial intelligence bring in a new age of antibiotic drug discovery?
Using machine-learning, researchers have discovered a new antibiotic that is able to kill bacteria resistant to other antibiotics.
Does drug tolerance promote antibiotic resistance despite combination therapy?
When investigating the effect tolerance to a single drug has when combination therapy is being used to prevent antibiotic resistance, a team of researchers demonstrated that antimicrobial tolerance can promote resistance.
US FDA approves first siderophore antibiotic, cefiderocol (Fetroja)
The US FDA has approved cefiderocol (Fetroja), a siderophore cephalosporin that inhibits bacterial cell wall synthesis. Fetroja is the first approved antibiotic that functions as a siderophore.
Antibiotic-loaded nanomesh developed for drug delivery
Researchers have developed nanomeshes as an effective drug-delivery system for antibiotics.
A peek behind the paper – Shujuan Sun on using existing antibiotics as antifungals
Take a look behind the scenes of a recent Future Microbiology review, entitled ‘Anti-Candida activity of existing antibiotics and their derivatives when used alone or in combination with antifungals’ as we ask the authors about Candida infections, the potential repurposing of antibiotics and the future of this field.
IDWeek: Antibiotics before dental visits are overprescribed and increase the risk of side effects
Research has suggested that prophylactic antibiotics are overprescribed before dental visits, and that taking them could actually increase the likelihood of adverse effects.
Combating resistance while maintaining innovation: The future of antimicrobial stewardship
In this perspective piece for Future Microbiology the authors argue that there is a lack of innovation to meet the current shortcomings of antibiotic R&D.