Highlights of the CDC’s 2019 antibiotic resistance threats report
The CDC has released an updated report outlining the burden of antimicrobial resistance in the USA and the greatest threats that face this country.
Browsing: Antimicrobial Resistance
Bacteriophage: alternative medicine or an evidence-based alternative?
Bacteriophage have been touted as the solution for antibiotic resistant microbes, why are they not being used in mainstream medicine?
Could game theory be used to predict antibiotic resistance genes?
Researchers have developed a game theory approach and a machine learning algorithm to accurately identify antibiotic resistance genes in bacteria.
Bacteria can lose cell walls in order to resist antibiotics
Researchers have observed a bacterial mechanism that allows bacteria to change form and resist antibiotics, without the transfer of resistance genes.
Combating resistance while maintaining innovation: The future of antimicrobial stewardship
In this perspective piece for Future Microbiology the authors argue that there is a lack of innovation to meet the current shortcomings of antibiotic R&D.
Multidrug efflux systems: information on evolution and mechanisms uncovered
Researchers have discovered that a relatively ancient drug efflux pump from Haemophilus influenzae exports the same antibiotics as its evolved counterpart from Escherichia coli, but was mitigated by a leaky porin channel.
A peek behind the paper – Sidharth Chopra on drug repurposing to tackle antimicrobial resistance
Take a look behind the scenes of a recent Future Microbiology review, entitled ‘An update on drug repurposing: Is it useful for tacking antimicrobial resistance?’ as we ask the authors about what challenges and limitations drug repurposing faces, in addition to why this strategy could be a promising alternative to the traditional drug discovery pipeline.
Coagulation factors show activity against drug-resistant Gram-negative bacteria
Coagulation factors, which normally function to clot blood, have been demonstrated to have antibacterial action against Gram-negative bacteria in vitro and in mouse models.
Malaria: genomic surveillance detects multi-drug resistance has spread in Asia
Multidrug resistance to two antimalarials, used in combination as a first-line therapy, has been found using genomic surveillance to be rapidly spreading throughout Asia.
Infographic: Gonorrhea – a timeline of resistance and it’s mechanisms
In this infographic we give you a visual snapshot of the antibiotics introduced for gonorrhea and a timeline of when resistance was first identified, in addition to setting out some of the primary resistance mechanisms.
