Researchers have developed a drug delivery system that could allow antiretroviral drugs for HIV to be administered only once a week, potentially making it easier for patients to adhere to drug regimens.
Browsing: Antiretroviral Therapy
Despite significant advances in the treatment of human immunodeficiency virus (HIV), there remain challenges. This review highlights recent advances in the application of nanotechnology to drug delivery, specifically with the purpose of improving HIV therapy.
A child born with HIV has been found to suppress the infection without the reliance on conventional antiretroviral therapy; this may have future implications on the therapeutic approaches to HIV especially in infants.
The comparative effectiveness of antiretroviral therapies for HIV: evidence to inform precision public health
This Editorial discusses a Health Economics and Outcomes Research (HEOR) approach to use a formal comparative effectiveness analysis and a network meta-analysis for both first- and second-line ART regimens for adults, adolescents and children.
Researchers have demonstrated in mouse models that HIV can persist in infected macrophages despite antiretroviral therapy, suggesting a new cell reservoir.
Researchers have demonstrated that utilizing nanoparticle formulated antiretrovirals could reduce the drug dose required in HIV patients, potentially cutting costs and improving treatment regimens.
Even in the era of antiretroviral treatment, mucosal candidiasis remains one of the most common manifestations in HIV-infected subjects. This editorial discusses the loss of immune control that allows mucosal candidiasis to occur.
Nanodrug formulations to enhance HIV drug exposure in lymphoid tissues and cells: clinical significance and potential impact on treatment and eradication of HIV/AIDS
In this review the authors discuss the limitations of current oral combination antiretroviral therapy and advances in anti-HIV nanoformulations.