AGO4: a potential new universal target for antiviral therapeutics
A team of researchers have uncovered a protein, AGO4, which may have the potential to be used as a therapeutic target to universally increase protection against viral pathogens.
Browsing: Antivirals
CARVER: CRISPR–Cas13 system kills viruses in human cells
A team from the Broad Institute at MIT and Harvard have designed a Cas13–CRISPR construct, termed CARVER, that can detect and kill viruses inside human cells. The flexible CARVER system could be used as a new tool in research and the clinic.
Polio, picornaviruses and publicizing science – an interview with Vincent Racaniello
In this interview we speak to Vincent Racaniello, Professor of Microbiology & Immunology, about his work on polio, picornaviruses and publicizing science through blogs and podcasts.
A peek behind the paper – Shitao Li on TRIM proteins as antivirals
Take a look behind the scenes of a recent Future Virology review, entitled: ‘TRIM proteins: an emerging antiviral protein family’, as we ask the authors about TRIM proteins, viral resistance and the future of this field.
A peek behind the paper – Peter Barlow on antivirals for human rhinovirus infections
Take a look behind the scenes of a recent Future Virology review entitled ‘Antiviral therapeutic approaches for human rhinovirus infections’ as we ask author Peter Barlow about antivirals, antibodies and the host response.
Gold nanoparticles present a potential broad-spectrum antiviral
Researchers have pioneered novel, gold nanoparticles, which bind and deform viruses rendering them inactive, thereby presenting potential in the development of a broad-spectrum antiviral.
Targeting human proteins: a new insight into HIV treatment
Researchers have identified a new treatment approach for acute HIV-infected patients, which targets human proteins rather than the virus.
First 3D movie of virus depicts key biological processes in replication
For the first time, physicists have created a 3D movie that demonstrates a virus preparing to infect a healthy cell via genomic rearrangement – leading to the potential to better treat an array of human diseases caused by viruses.
Identifying novel antiviral targets against enterovirus 71: where are we?
This review aims to provide a better understanding of HEV71 virology and potential antivirals for progressive clinical development with respect to their elucidated mechanistic actions.
Is hepatitis C fully treatable with oral direct-acting agents?
A new systematic evidence review has discovered that FDA-approved direct-acting antiviral regimens are effective against all genotypes of hepatitis C.