Graham Hatfull speaks about heading up the SEA-PHAGES project and the role this has played in understanding phage diversity and evolution, in addition to commenting on a recent case where a phage cocktail was used to treat a case of Mycobacterium abscessus.
A novel phage-based blood assay has demonstrated its potential for identifying people at high-risk of developing tuberculosis, in addition to diagnosing established cases.
Researchers from the New York Institute of Technology (NYIT, NY, USA) have discovered and characterized two bacteriophages from kitchen sponges.
Phage therapy using genetically engineered bacteriophages has treated a 15-year-old girl who developed a drug-resistant infection following a lung transplant, as outlined in Nature Medicine.
Pseudomonas aeruginosa uses a phage to trick the host’s immune system into ignoring it, in turn suppressing bacterial clearance from infected wounds, according to new research.
A first for clinical trials in the US as researchers from the University of California San Diego School of Medicine get US FDA approval to use intravenously-administered bacteriophage therapy in hopes of combatting resistant bacteria.
A bacteriophage, VP882, has been identified to use bacterial quorum-sensing as a method to control the lysis-lysogeny decision. This is the first time a virus has been shown to detect a bacterial molecule.
In recent years, researchers have discovered the potential of CRISPR as an antimicrobial. In this blog post we explain the recent advances made in this field and the different approaches by which CRISPR can be used as a new weapon in the battle against antimicrobial resistance.
Scientists, led by the National University of Singapore and the University of Glasgow, have used the term ‘lateral transduction’ to describe a novel, dangerously-potent mechanism of bacteriophage-induced genetic transduction.
Researchers demonstrate for the first time the importance of bacteriophages in the development of multifactorial diseases such as Parkinson’s, a potentially critical factor that has been previously over-looked.