Discover more about the two routes phage therapy could take, the standardized drug approach and the personalized medicine approach, and whether either could make it to the clinic.
Bacteriophage have been touted as the solution for antibiotic resistant microbes, why are they not being used in mainstream medicine?
In this opinion piece we take a look at the interaction of bacteria, phages and the human immune system. asking how these three components each play a role in phage therapy?
Graham Hatfull speaks about heading up the SEA-PHAGES project and the role this has played in understanding phage diversity and evolution, in addition to commenting on a recent case where a phage cocktail was used to treat a case of Mycobacterium abscessus.
A novel phage-based blood assay has demonstrated its potential for identifying people at high-risk of developing tuberculosis, in addition to diagnosing established cases.
Researchers from the New York Institute of Technology (NYIT, NY, USA) have discovered and characterized two bacteriophages from kitchen sponges.
Phage therapy using genetically engineered bacteriophages has treated a 15-year-old girl who developed a drug-resistant infection following a lung transplant, as outlined in Nature Medicine.
Pseudomonas aeruginosa uses a phage to trick the host’s immune system into ignoring it, in turn suppressing bacterial clearance from infected wounds, according to new research.
A first for clinical trials in the US as researchers from the University of California San Diego School of Medicine get US FDA approval to use intravenously-administered bacteriophage therapy in hopes of combatting resistant bacteria.
A bacteriophage, VP882, has been identified to use bacterial quorum-sensing as a method to control the lysis-lysogeny decision. This is the first time a virus has been shown to detect a bacterial molecule.